Autophagy is a major intracellular degradation/recycling system ubiquitous in eukaryotic
cells. It contributes to the turnover of cellular components by delivering portions of the …

Based on a functional categorization, proteins may be grouped into three types and sorted to
either the proteasome or the macroautophagy pathway for degradation. The two pathways …

Autophagy is a self‐digesting mechanism responsible for removal of damaged organelles,
malformed proteins during biosynthesis, and nonfunctional long‐lived proteins by lysosome …

Autophagy is an intracellular pathway for bulk protein degradation and the removal of
damaged organelles by lysosomes. Autophagy was previously thought to be unselective; …

Autophagy is a cellular process whose primary function is to degrade long-lived proteins
and recycle cellular components. Beside macroautophagy, there are several forms of …

Mounting evidence suggests that autophagy is a more selective process than originally
anticipated. The discovery and characterization of autophagic adapters, like p62 and NBR1 …

Macroautophagy is a bulk degradation process characterised by the formation of double-
membrane vesicles, called autophagosomes, which deliver cytoplasmic substrates for …

Autophagy is an essential cellular mechanism which plays “housekeeping” role in normal
physiological processes including removing of long lived, aggregated and misfolded …

Autophagy is a conserved intracellular pathway that delivers cytoplasmic contents to
lysosomes for degradation via double-membrane autophagosomes. Autophagy substrates …

Autophagy, a process of cellular self-digestion, delivers intracellular components including
superfluous and dysfunctional proteins and organelles to the lysosome for degradation and …