Antigen presentation: Influence of Cell Type and Route of Antigen Uptake

AO Kamphorst - 2011 - digitalcommons.rockefeller.edu
Abstract" Dendritic cells (DCs), which maintain tolerance and orchestrate T cell immune
responses, comprise a heterogeneous group of cells. For example, in the steady state …

Route of antigen uptake differentially impacts presentation by dendritic cells and activated monocytes

AO Kamphorst, P Guermonprez, D Dudziak… - The Journal of …, 2010 - journals.aai.org
Dendritic cells (DCs), which maintain tolerance and orchestrate T cell immune responses,
comprise a heterogeneous group of cells. For example, in the steady state, murine spleen …

[PDF][PDF] ANTIGEN HANDLING BY DENDRITIC CELLS

N HO - scholarlypublications …
Dendritic cells (DCs) are professional antigen presenting cells (APCs) that can capture,
process and present exogenous antigen on MHC class I (MHCI) molecules. This cross …

Antigen cross-presentation by dendritic cell subsets: one general or all sergeants?

S Nierkens, J Tel, E Janssen, GJ Adema - Trends in immunology, 2013 - cell.com
Antigen cross-presentation describes the process through which dendritic cells (DCs)
acquire exogenous antigens for presentation on MHC class I molecules. The ability to cross …

Antigen processing and CD24 expression determine antigen presentation by splenic CD4+ and CD8+ dendritic cells

D Askew, CV Harding - Immunology, 2008 - Wiley Online Library
To examine heterogeneity in dendritic cell (DC) antigen presentation function, murine
splenic DCs were separated into CD4+ and CD8+ populations and assessed for the ability …

Sustained cross‐presentation capacity of murine splenic dendritic cell subsets in vivo

NI Ho, MGM Camps, EFE de Haas… - European journal of …, 2018 - Wiley Online Library
An exclusive feature of dendritic cells (DCs) is their ability to cross‐present exogenous
antigens in MHC class I molecules. We analyzed the fate of protein antigen in antigen …

Cross-presentation by human dendritic cell subsets

E Segura, S Amigorena - Immunology letters, 2014 - Elsevier
Dendritic cells (DCs) are a heterogeneous population of professional antigen-presenting
cells. Several murine DC subsets differ in their phenotype and functional properties, in …

Antigen presentation and T cell stimulation by dendritic cells

P Guermonprez, J Valladeau, L Zitvogel… - Annual review of …, 2002 - annualreviews.org
Dendritic cells take up antigens in peripheral tissues, process them into proteolytic peptides,
and load these peptides onto major histocompatibility complex (MHC) class I and II …

Antigen capture, processing, and presentation by dendritic cells: recent cell biological studies

RM Steinman, K Inaba, S Turley, P Pierre, I Mellman - Human immunology, 1999 - Elsevier
Antigen uptake, processing and presentation by dendritic cells [DCs] have become
amenable to cell biological approaches. The critical events occur in DCs that are …

Antigen presentation by dendritic cells in vivo

E Segura, JA Villadangos - Current opinion in immunology, 2009 - Elsevier
Dendritic cells (DC) are heterogenous, comprising several subpopulations of migratory and
lymphoid-organ-resident types. Recent studies addressing the role of each subset in antigen …