Recent advances in understanding the mechanisms of PM2. 5-mediated neurodegenerative diseases

X Zhu, X Ji, Y Shou, Y Huang, Y Hu, H Wang - Toxicology Letters, 2020 - Elsevier
PM 2.5 particles are widely believed to be associated with respiratory and cardiovascular
diseases. However, recent studies have reported that PM 2.5 may be associated with …

Exposure to PM2. 5 induces neurotoxicity, mitochondrial dysfunction, oxidative stress and inflammation in human SH-SY5Y neuronal cells

CH Lin, CJB Nicol, C Wan, SJ Chen, RN Huang… - Neurotoxicology, 2022 - Elsevier
Ambient air pollution is a global public health issue. Recent evidence suggests that
exposure to fine aerosolized particulate matter (PM) as small as≤ 2.5 microns (PM 2.5) is …

Possible association between PM2. 5 and neurodegenerative diseases: A systematic review

A Cristaldi, M Fiore, GO Conti, E Pulvirenti… - Environmental …, 2022 - Elsevier
Air pollution is one of the most serious environmental problems that afflict our planet and
one of the greatest risk factors for human health. In particular, PM 2.5 is able to cross the …

Neurotoxicity of the air-borne particles: from molecular events to human diseases

F Liu, C Liu, Y Liu, J Wang, Y Wang, B Yan - Journal of Hazardous Materials, 2023 - Elsevier
Exposure to PM 2.5 is associated with an increased incidence of CNS diseases in humans,
as confirmed by numerous epidemiological studies. Animal models have demonstrated that …

[HTML][HTML] Microglial Activation and Oxidative Stress in PM2.5-Induced Neurodegenerative Disorders

J Song, K Han, Y Wang, R Qu, Y Liu, S Wang, Y Wang… - Antioxidants, 2022 - mdpi.com
Fine particulate matter (PM2. 5) pollution remains a prominent environmental problem
worldwide, posing great threats to human health. The adverse effects of PM2. 5 on the …

Progress in Mechanisms, Pathways and Cohort Studies About the Effects of PM2.5 Exposure on the Central Nervous System

M Ye, J Yang, J Li, Y Wang, W Chen, L Zhu… - Reviews of …, 2023 - Springer
An increasing number of studies have shown that particulate matter (PM) exposure can
produce damaging effects on respiratory and cardiovascular systems, however, whether PM …

Neurodevelopmental toxicity induced by PM2. 5 Exposure and its possible role in Neurodegenerative and mental disorders

X Liu, J Huang, C Song, T Zhang… - Human & …, 2023 - journals.sagepub.com
Recent extensive evidence suggests that ambient fine particulate matter (PM2. 5, with an
aerodynamic diameter≤ 2.5 μm) may be neurotoxic to the brain and cause central nervous …

Exposure to PM2. 5 aggravates Parkinson's disease via inhibition of autophagy and mitophagy pathway

Y Wang, C Li, X Zhang, X Kang, Y Li, W Zhang, Y Chen… - Toxicology, 2021 - Elsevier
Extensive health studies had declared that exposure to particulate matter (PM) was closely
associated with neurodegenerative diseases, ie Parkinson's disease (PD). Our aim was to …

Ambient PM2. 5 chronic exposure leads to cognitive decline in mice: From pulmonary to neuronal inflammation

Y Shou, X Zhu, D Zhu, H Yin, Y Shi, M Chen, L Lu… - Toxicology letters, 2020 - Elsevier
Abstract Fine particulate matter 2.5 (PM 2.5), one of the main components of air pollutants,
seriously threatens human health. Possible neuronal dysfunction induced by PM 2.5 has …

[HTML][HTML] A review of respirable fine particulate matter (PM2.5)-induced brain damage

W Li, G Lin, Z Xiao, Y Zhang, B Li, Y Zhou… - Frontiers in Molecular …, 2022 - frontiersin.org
Respirable fine particulate matter (PM2. 5) has been one of the most widely publicized
indicators of pollution in recent years. Epidemiological studies have established a strong …