Nephrotic syndrome is not a single disease; rather, it is a term for numerous diseases and
pathological types. Renal biopsy is of use in determining the diagnosis and prognosis, and …

The kidney glomerulus is the site of plasma filtration and production of primary urine in the
kidney. The structure not only plays a pivotal role in ultrafiltration of plasma into urine but …

Renal biopsy remains the gold standard test for definitive diagnosis of glomerular diseases.
This invasive procedure; however, has a potential risk for serious complications and is …

Urine is a biological material that can be easily obtained in the clinic. The identification of
proteins excreted in urine provides useful biological information about the kidney as well as …

The World Health Organization has estimated mortality and burden of chronic kidney
disease (CKD) in 2002 and predicted it will rank 13th in 2030 instead of 17th in 2002 among …

Introduction Chronic kidney disease is avery common and complex chronic disease.
Uncovering the pathological patterns of CKD on the molecular level of bio-fluids and tissue …

Abstract Treatment effectiveness for kidney disease is limited by lack of accuracy, sensitivity,
specificity of diagnostic, prognostic, and therapeutic biomarkers. The gold standard test …

Background. Nephrotic syndrome is a condition that is clinically associated with poor
outcome. In this study, we compared different techniques of urine sample preparation in …

The analysis of protein biomarkers in urine is expected to lead to advances in a variety of
clinical settings. Several characteristics of urine including a low-protein matrix, ease of …

Urine has been in the center of attention among scientists of clinical proteomics in the past
decade, because it is valuable source of proteins and peptides with a relative stable …