Resveratrol distinctively modulates the inflammatory profiles of immune and endothelial cells

J Schwager, N Richard, F Widmer… - BMC Complementary and …, 2017 - Springer
Background The phenolic substance resveratrol (RES) is a plant metabolite known to
modulate numerous physiological functions and to exert beneficial effects as a cancer …

Antiatherogenic effect of resveratrol attributed to decreased expression of ICAM-1 (Intercellular adhesion Molecule-1) mechanistic link from focal adhesion to …

Y Seo, J Park, W Choi, D Ju Son… - … , and vascular biology, 2019 - Am Heart Assoc
Objective—Increasing evidence shows that resveratrol has antiatherogenic effects, but its
underlying mechanisms are unknown. Thus, we evaluated the molecular mechanisms …

The protective roles of citrus flavonoids, naringenin, and naringin on endothelial cell dysfunction in diseases

JA Adetunji, KD Fasae, AI Awe, OK Paimo… - Heliyon, 2023 - cell.com
The endothelial cells (ECs) make up the inner lining of blood vessels, acting as a barrier
separating the blood and the tissues in several organs. ECs maintain endothelium integrity …

[HTML][HTML] Resveratrol Inhibits TNF-α–Induced Proliferation and Matrix Metalloproteinase Expression in Human Vascular Smooth Muscle Cells

B Lee, SK Moon - The Journal of nutrition, 2005 - Elsevier
Resveratrol (RV), a polyphenolic substance found in grape skin, was suggested to play a
role in preventing the development of atherosclerotic disease. Although RV has …

Beneficial effects of resveratrol administration—Focus on potential biochemical mechanisms in cardiovascular conditions

M Wiciński, M Socha, M Walczak, E Wódkiewicz… - Nutrients, 2018 - mdpi.com
Resveratrol (RV) is a natural non-flavonoid polyphenol and phytoalexin produced by a
number of plants such as peanuts, grapes, red wine and berries. Numerous in vitro studies …

Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase

T Wallerath, G Deckert, T Ternes, H Anderson, H Li… - Circulation, 2002 - Am Heart Assoc
Background—Estrogens can upregulate endothelial nitric oxide synthase (eNOS) in human
endothelial cells by increasing eNOS promoter activity and enhancing the binding activity of …

Cellular and molecular effects of resveratrol in health and disease

W Yu, YC Fu, W Wang - Journal of cellular biochemistry, 2012 - Wiley Online Library
Resveratrol, a natural polyphenol abundantly found in grape skins and red wine, possesses
diverse biochemical and physiological actions, including anti‐inflammatory, anti‐oxidation …

Resveratrol suppresses IL-6-induced ICAM-1 gene expression in endothelial cells: effects on the inhibition of STAT3 phosphorylation

BS Wung, MC Hsu, CC Wu, CW Hsieh - Life Sciences, 2005 - Elsevier
Resveratrol, a polyphenolic phytoaxelin present in red wine, has been suggested to protect
against atherosclerosis and cardiovascular disease because of its antioxidant effects …

Resveratrol prevents monocrotaline-induced pulmonary hypertension in rats

A Csiszar, N Labinskyy, S Olson, JT Pinto, S Gupte… - …, 2009 - Am Heart Assoc
Proliferation of pulmonary arterial smooth muscle cells, endothelial dysfunction, oxidative
stress, and inflammation promotes the development of pulmonary hypertension. Resveratrol …

Resveratrol and anti-atherogenic effects

G Riccioni, MA Gammone, G Tettamanti… - … Journal of Food …, 2015 - Taylor & Francis
The role of inflammation and oxidative stress in atherosclerosis development has been
increasingly well recognized over the past decade. Inflammation has a significant role at all …