[HTML][HTML] The effect of resveratrol on the cardiovascular system from molecular mechanisms to clinical results

R Gal, L Deres, K Toth, R Halmosi, T Habon - International journal of …, 2021 - mdpi.com
Cardiovascular diseases are the leading causes of death worldwide. The cardioprotective
effects of natural polyphenols such as resveratrol (3, 5, 4-trihydroxystilbene) have been …

Resveratrol ameliorates arterial stiffness assessed by cardio-ankle vascular index in patients with type 2 diabetes mellitus

H Imamura, T Yamaguchi, D Nagayama… - International heart …, 2017 - jstage.jst.go.jp
Resveratrol has been reported to have potent anti-atherosclerotic effects in animal studies.
However, there are few interventional studies in human patients with atherosclerogenic …

Resveratrol: a natural polyphenol with multiple chemopreventive properties

F Brisdelli, G D'Andrea, A Bozzi - Current drug metabolism, 2009 - ingentaconnect.com
Resveratrol, a naturally occurring polyphenol, shows pleiotropic health beneficial effects,
including antioxidant, anti-inflammatory, anti-aging, cardioprotective and neuroprotective …

The protective effect of resveratrol on vascular aging by modulation of the renin–angiotensin system

EN Kim, MY Kim, JH Lim, Y Kim, SJ Shin, CW Park… - Atherosclerosis, 2018 - Elsevier
Background and aims This study evaluated the effects of resveratrol on arterial aging and
the renin–angiotensin system (RAS) in mice and vascular smooth muscle cells (VSMCs) …

Resveratrol improves cardiovascular function in DOCA-salt hypertensive rats

V Chan, A Fenning, A Iyer, A Hoey… - Current Pharmaceutical …, 2011 - ingentaconnect.com
The phytoalexin resveratrol (3, 4', 5-trihydroxy-trans-stilbene) may attenuate cardiovascular
disease in man. This study has determined whether treatment with resveratrol (1 mg/kg/day …

Resveratrol modulates angiogenesis through the GSK3β/β-catenin/TCF-dependent pathway in human endothelial cells

H Wang, H Zhou, Y Zou, Q Liu, C Guo, G Gao… - Biochemical …, 2010 - Elsevier
Vascular endothelial growth factor (VEGF) plays a critical role in angiogenesis due to its
potent and specific ability to promote the proliferation and migration of endothelial cells …

Trans-but not Cis-resveratrol impairs angiotensin-II–mediated vascular inflammation through inhibition of NF-κB activation and peroxisome proliferator-activated …

C Rius, M Abu-Taha, C Hermenegildo… - The Journal of …, 2010 - journals.aai.org
Abstract Angiotensin II (Ang-II) displays inflammatory activity and is implicated in several
cardiovascular disorders. This study evaluates the effect of cis-and trans (t)-resveratrol …

Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells

UGB Haider, D Sorescu, KK Griendling… - Molecular …, 2002 - ASPET
Resveratrol (RV), a polyphenolic substance found in grape skin, is proposed to account in
part for the protective effect of red wine in the cardiovascular system. Angiotensin II (Ang II) …

Resveratrol ameliorates myocardial damage by inducing vascular endothelial growth factor-angiogenesis and tyrosine kinase receptor Flk-1

S Fukuda, S Kaga, L Zhan, D Bagchi, DK Das… - Cell biochemistry and …, 2006 - Springer
In our study, resveratrol (polyphenol) has been identified as a very important stimulus/agent
for the induction of new vessel growth. Occlusion of a main coronary depletes the blood …

[HTML][HTML] Preclinical and clinical evidence for the role of resveratrol in the treatment of cardiovascular diseases

BNM Zordoky, IM Robertson, JRB Dyck - Biochimica et Biophysica Acta …, 2015 - Elsevier
Cardiovascular disease is the leading cause of death worldwide. Despite advancements in
diagnosis and treatment of cardiovascular disease, the incidence of cardiovascular disease …