The evolution of the nucleus imposed on eukaryotic cells the necessity to strictly control
exchange of molecules between the nucleus and the remainder of the cell, not only to …

In eukaryotic cells, cell functions are maintained in an orderly manner through the
continuous traffic of various proteins between the cell nucleus and the cytoplasm. The …

Protein export from the nucleus of eukaryotic cells serves three main purposes:(1) to remove
factors that are only transiently required in the nucleus-transcriptional signaling molecules …

Molecules enter and exit the nucleus of eukaryotic cells through aqueous channels formed
in the nuclear envelope by nuclear pore complexes (NPC). Proteins entering or leaving the …

In eukaryotes, the nuclear membrane provides a physical barrier to the passive diffusion of
macromolecules from and into the cytoplasm. Nucleocytoplasmic traffic occurs through …

Nucleocytoplasmic transport is an essential process in eukaryotes. The molecular
mechanisms underlying nuclear transport that involve the nuclear transport receptor, small …

Understanding how macromolecules are rapidly exchanged between the nucleus and the
cytoplasm through nuclear pore complexes is a fundamental problem in biology. Exportins …

抄録 The active transport of proteins into and out of the nucleus is mediated by specific
signals, the nuclear localzation signal (NLS) and nuclear export signal (NES), respectively …

Transport of macromolecules into and out of the nucleus is generally effected by targeting
signals that are recognized by specific members of the importin/exportin transport receptor …

▪ Abstract The compartmentation of eukaryotic cells requires all nuclear proteins to be
imported from the cytoplasm, whereas, for example, transfer RNAs, messenger RNAs, and …