We assessed the diagnostic usefulness of adding anti-CD117 to our existing flow cytometric
profile in the analysis of 150 consecutive cases of acute leukemia (de novo or relapsed …

Background The issue of which specific antibodies need to be used when evaluating acute
leukemias by flow cytometry is controversial. Methods Recent studies have suggested that …

The c-kit proto-oncogene encodes a 145 kd tyrosyne kinase transmembrane receptor, which
plays a key role in haemopoiesis. The c-kit has been classified as CD117 and is especially …

Abstract C-kit receptor (CD117) and its ligand, stem cell factor, play a key role in normal
hematopoiesis. It has been demonstrated that its expression extremely increases in …

Acute myelogenous leukemia (AML) is a deadly disease characterized by high relapse rates
even in patients who initially achieve complete remission. Standard therapy for AML has …

A total of 49 newly diagnosed patients with acute leukemia were studied in order to assess
the diagnostic value of clone AC141 of CD133 antibody by flow cytometry. AC141 …

CD117 is a transmembrane protein receptor encoded by the c-kit protooncogene. The
CD117 ligand is stem cell factor, an important hematopoietic regulator. CD117 is present on …

We evaluated the lineage specificity of CD79a in acute leukemias using 3-color flow
cytometry in 58 consecutive cases. A panel of cell-surface antigens, including myeloid …

We estimated by quantitative flow cytometry (FC) the expression of CD13, CD33, CD34 and
CD117 antigens in cells from 64 patients with acute myeloid leukaemia (AML) and 22 …

Anti-CD34 is a monoclonal antibody that reacts with bone marrow progenitor cells and
leukemic blasts, and is expressed on 30% to 50% of all acute leukemias. Detection of CD34 …