Background and Purpose—Stroke is a major cause of death and disability, and it is
imperative to develop therapeutics to mitigate stroke-related injury. Despite many promising …

Stroke is the leading cause of adult disability and death worldwide. Mitochondrial
dysfunction has been recognized as a marker of neuronal death during ischemic stroke …

Stroke is one of the main causes of mortality and disability in most countries of the world.
The only way of managing patients with ischemic stroke is the use of intravenous tissue …

Stroke is the leading cause of adult disability and mortality in most developing and
developed countries. The current best practices for patients with acute ischemic stroke …

Stroke is the leading cause of death and adult disability worldwide. Mitochondrial
dysfunction has been regarded as one of the hallmarks of ischemia/reperfusion (I/R) …

Stroke is the leading cause of death and physical disability worldwide. Mitochondrial
dysfunction has been considered as one of the hallmarks of ischemic stroke and contributes …

Stroke remains a major cause of death and disability in the United States and around the
world. Solid safety and efficacy profiles of novel stroke therapeutics have been generated in …

Evidence obtained over the past two decades shows that reactive oxygen species (ROS) are
involved in brain lesions, including those due to cerebral ischemia-reperfusion. The …

Stroke is the fourth leading cause of death and the leading cause of long-term disability in
the United States. Blood flow deficit results in an expanding infarct core with a time-sensitive …

Stroke is a main cause of mortality and morbidity worldwide. Despite the increasing
development of innovative treatments for stroke, most are unsuccessful in clinical trials. In …