It is largely unknown how invading autoreactive T cells initiate the pathogenic process inside
the diseased organ in organ-specific autoimmune diseases. In experimental autoimmune …

Background It is not clear how invading autoreactive T cells initiate the pathogenic process
inside the diseased organ in T cell-mediated organ-specific autoimmune disease. In …

It is largely unknown how invading autoreactive T cells initiate the pathogenic process inside
the diseased organ in organ-specific autoimmune disease. In this study, we used a chronic …

purpose. To investigate whether high mobility group box protein (HMGB)-1, acting as a
novel proinflammatory cytokine, is involved in experimental autoimmune uveoretinitis (EAU) …

High‐mobility group box 1 (HMGB1) is a nuclear protein that can also act as an extracellular
trigger of inflammation, proliferation, and migration in eye diseases. It induces signaling …

Purpose Extracellular high mobility group box 1 (HMGB1) acts as a damage associated
molecular pattern molecule through the Toll-like receptor to promote autoreactive B cell …

Purpose: To determine high-mobility group box 1 (HMGB1) expression during experimental
dry eye (EDE) and dry eye-like culture conditions and elucidate its role in corneal dry eye …

Background High-mobility group box 1 protein (HMGB1) is recently described as a late
mediator of lethal endotoxemia with proinflammatory cytokine-like properties. The purpose …

High-mobility group box 1 (HMGB1) functions as a transcription-enhancing nuclear protein
as well as a crucial cytokine that regulates inflammation. This study demonstrated that …

Purpose: High-mobility group proteins are chromatin-binding factors with key roles in
nuclear homeostasis. Evidence indicates that extracellularly released high-mobility group …