Curcumin anticancer studies in pancreatic cancer

S Bimonte, A Barbieri, M Leongito, M Piccirillo… - Nutrients, 2016 - mdpi.com
Pancreatic cancer (PC) is one of the deadliest cancers worldwide. Surgical resection
remains the only curative therapeutic treatment for this disease, although only the minority of …

[HTML][HTML] Therapeutic applications of curcumin for patients with pancreatic cancer

M Kanai - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
A number of preclinical studies have demonstrated anticancer effects for curcumin in various
types of tumors, including pancreatic cancer. Curcumin has anticancer effects both alone …

Therapeutic potential of curcumin in treatment of pancreatic cancer: current status and future perspectives

M Hosseini, SM Hassanian… - Journal of cellular …, 2017 - Wiley Online Library
Pancreatic cancer is among the leading cause of deaths due to cancer with extremely poor
prognosis. Gemcitabine is being used in the treatment of patient with pancreatic ductal …

Curcumin and gemcitabine in patients with advanced pancreatic cancer

R Epelbaum, M Schaffer, B Vizel, V Badmaev… - Nutrition and …, 2010 - Taylor & Francis
Curcumin has a potent antiproliferative activity and can also potentiate the antitumor effect of
gemcitabine. This study was undertaken to evaluate the activity and feasibility of …

Phase II trial of curcumin in patients with advanced pancreatic cancer

N Dhillon, BB Aggarwal, RA Newman, RA Wolff… - Clinical cancer …, 2008 - AACR
Purpose: Pancreatic cancer is almost always lethal, and the only US Food and Drug
Administration–approved therapies for it, gemcitabine and erlotinib, produce objective …

Curcumin analogs: Their roles in pancreatic cancer growth and metastasis

GP Nagaraju, L Benton, SR Bethi… - … Journal of Cancer, 2019 - Wiley Online Library
Curcumin is a polyphenolic constituent of turmeric that is known to have various molecular
effects in preclinical models, leading to prevention and anticancer properties. In clinical …

[PDF][PDF] The dark side of curcumin

E Burgos‐Morón, JM Calderón‐Montaño… - International journal of …, 2010 - Citeseer
Dear Editor, Curcumin is a yellow–orange pigment obtained from the plant Curcuma longa.
The powdered rhizome of this plant, called turmeric, is a common ingredient in curry …

Exploring the contribution of curcumin to cancer therapy: A systematic review of randomized controlled trials

C De Waure, C Bertola, G Baccarini, M Chiavarini… - Pharmaceutics, 2023 - mdpi.com
Although the anticancer role of curcumin has been extensively addressed in preclinical
research, only a few studies were carried out in humans, with conflicting results. The aim of …

[HTML][HTML] Curcumin enhances anti‑cancer efficacy of either gemcitabine or docetaxel on pancreatic cancer cells

P Liu, Q Ying, H Liu, SQ Yu, LP Bu… - Oncology …, 2020 - spandidos-publications.com
Curcumin is a natural compound extracted from turmeric (Curcuma longa), which has been
reported to be a promising anti‑cancer drug in various human cancers. However, the effects …

Synergistic effect of garcinol and curcumin on antiproliferative and apoptotic activity in pancreatic cancer cells

MA Parasramka, SV Gupta - Journal of oncology, 2012 - Wiley Online Library
Pancreatic cancer (PaCa) is a major health concern due to its aggressiveness and early
metastasis. Current treatments for PaCa are limited by development of resistance against …