Efficacy and safety of extracranial vein angioplasty in multiple sclerosis: a randomized clinical trial

P Zamboni, L Tesio, S Galimberti, L Massacesi… - JAMA …, 2018 - jamanetwork.com
Importance Chronic cerebrospinal venous insufficiency (CCSVI) is characterized by
restricted venous outflow from the brain and spinal cord. Whether this condition is …

Extracranial venous hemodynamics in multiple sclerosis: a case-control study

G Tsivgoulis, M Mantatzis, C Bogiatzi, K Vadikolias… - Neurology, 2011 - AAN Enterprises
Objectives: A chronic state of impaired cerebral and cervical venous drainage, termed
chronic cerebrospinal venous insufficiency (CCSVI), has recently been implicated in the …

Significance of the internal jugular vein in the treatment of cerebrovascular insufficiency

DB Reid - Journal of Endovascular Therapy, 2011 - journals.sagepub.com
The significance of the safety report on endovascular treatment for chronic cerebrospinal
venous insufficiency (CCSVI) in patients with multiple sclerosis (MS) by Petrov et al. 1 …

Progressive multiple sclerosis is not associated with chronic cerebrospinal venous insufficiency

C Baracchini, P Perini, F Causin, M Calabrese… - Neurology, 2011 - AAN Enterprises
Objective: Chronic cerebrospinal venous insufficiency (CCSVI) had been suggested to play
a major pathogenetic role in multiple sclerosis (MS), but recent data on early stages of MS …

[HTML][HTML] Multiple sclerosis and CCSVI: a population-based case control study

F Patti, A Nicoletti, C Leone, S Messina, E D'Amico… - 2012 - journals.plos.org
Background Chronic cerebrospinal venous insufficiency (CCSVI) has been associated to
multiple sclerosis (MS). Objective To evaluate the possible association between CCSVI and …

Endovascular treatment of CCSVI in patients with multiple sclerosis: clinical outcome of 462 cases

A Ghezzi, P Annovazzi, E Cocco, G Coarelli… - Neurological …, 2013 - Springer
Although it is still debated whether chronic cerebro-spinal venous insufficiency (CCSVI)
plays a role in multiple sclerosis (MS) development, many patients underwent endovascular …

[HTML][HTML] Efficacy and safety of venous angioplasty of the extracranial veins for multiple sclerosis. Brave dreams study (brain venous drainage exploited against multiple …

P Zamboni, A Bertolotto, P Boldrini, P Cenni… - Trials, 2012 - Springer
Background Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the
central nervous system with a disabling progressive course. Chronic cerebrospinal venous …

Funding CCSVI research is/was a waste of valuable time, money and intellectual energy: yes

A Ghezzi - Multiple Sclerosis Journal, 2013 - journals.sagepub.com
In the case of CCSVI, all of these criteria are either not, or only partially, fulfilled: 5 a) the
discrepancy of results is against criterion 1; b) the lack of reproducibility against criterion 2 …

[HTML][HTML] Clinical characteristics, inflammation and coagulation status in patients with immunological disease-related chronic cerebrospinal venous insufficiency

SY Song, D Lan, XQ Wu, YC Ding, XM Ji… - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Background Immunological disease-related chronic cerebrospinal venous insufficiency
(CCSVI) is rarely reported. This study aimed to analyze clinical characteristics, inflammation …

Chronic cerebrospinal venous insufficiency and the doubtful promise of an endovascular treatment for multiple sclerosis

H Dorne, OO Zaidat, D Fiorella, J Hirsch… - Journal of …, 2010 - jnis.bmj.com
As neurointerventionalists interested in interventional treatment of neurological disorders, it
is time to take a thorough and objective look at CCSVI. This commentary will examine the …