Oxidative stress and ginsenosides: An update on the molecular mechanisms

B He, D Chen, X Zhang, R Yang, Y Yang… - Oxidative medicine …, 2022 - Wiley Online Library
Ginsenosides are a class of active components extracted from ginseng plants (such as
Panax ginseng, Panax quinquefolium, and Panax notoginseng). Ginsenosides have …

Pharmacological properties, molecular mechanisms and therapeutic potential of ginsenoside Rg3 as an antioxidant and anti-inflammatory agent

J Wang, L Zeng, Y Zhang, W Qi, Z Wang… - Frontiers in …, 2022 - frontiersin.org
Inflammation and oxidative stress lead to various acute or chronic diseases, including
pneumonia, liver and kidney injury, cardiovascular and cerebrovascular diseases, metabolic …

[HTML][HTML] Ginsenosides for therapeutically targeting inflammation through modulation of oxidative stress

S Paik, GY Song, EK Jo - International Immunopharmacology, 2023 - Elsevier
Ginsenosides are steroid glycosides derived from ginseng plants such as Panax ginseng,
Panax quinquefolium, and Panax notoginseng. Advances in recent studies have identified …

Ginsenoside Rb1 directly scavenges hydroxyl radical and hypochlorous acid

JM Lu, SM Weakley, Z Yang, M Hu… - Current …, 2012 - ingentaconnect.com
Reactive oxygen species (ROS) have been implicated in a variety of inflammatory diseases
including cardiovascular disease (CVD), cancer, diabetes, Alzheimer's disease, autism …

Pharmacodynamics of ginsenosides: antioxidant activities, activation of Nrf2, and potential synergistic effects of combinations

CLL Saw, AY Yang, DC Cheng… - Chemical Research …, 2012 - ACS Publications
Ginseng has long been used in Asian countries for more than 2000 years. Currently, in the
“Western World or Western Medicines”, many reports have indicated that they have used …

Chemical insights into ginseng as a resource for natural antioxidants

ZQ Liu - Chemical reviews, 2012 - ACS Publications
1. INTRODUCTION Ginseng is the root of Panax ginseng CA Meyer mainly produced in
China, Korea, and America. The first book recording ginseng is Shennongbencaojing about …

Antioxidant Activity of Panax ginseng to Regulate ROS in Various Chronic Diseases

MN Morshed, JC Ahn, R Mathiyalagan, EJ Rupa… - Applied Sciences, 2023 - mdpi.com
Reactive oxygen species (ROS)-the byproduct of regular cell activity formed by various
cellular components—play a significant role in pathological and physiological conditions …

[HTML][HTML] Role of ginsenosides, the main active components of Panax ginseng, in inflammatory responses and diseases

JH Kim, YS Yi, MY Kim, JY Cho - Journal of ginseng research, 2017 - Elsevier
Panax ginseng is one of the most universally used herbal medicines in Asian and Western
countries. Most of the biological activities of ginseng are derived from its main constituents …

Ginsenoside Re mitigates 6-hydroxydopamine-induced oxidative stress through upregulation of GPX4

GH Lee, WJ Lee, J Hur, E Kim, HG Lee, HG Seo - Molecules, 2020 - mdpi.com
Ginsenosides are active components found abundantly in ginseng which has been used as
a medicinal herb to modify disease status for thousands of years. However, the …

Ginsenoside CK targeting KEAP1-DGR/Kelch domain disrupts the binding between KEAP1 and NRF2-DLG motif to ameliorate oxidative stress damage

C Cheng, K Liu, Y Xu, F Shen, Y Han, Y Hou, T Zhang… - Phytomedicine, 2023 - Elsevier
Abstract Background Panax ginseng and Panax notoginseng as traditional Chinese
medicines, are widely used in the treatment of qi deficiency, viral or bacterial infection …