Peptides and drug delivery

KR Ulapane, BM Kopec, MEG Moral… - Peptides and peptide …, 2017 - Springer
Peptides have been used as drugs to treat various health conditions, and they are also
being developed as diagnostic agents. Due to their receptor selectivity, peptides have …

Recent advances in delivery of peptide and protein therapeutics to the brain

S Arora, T Bajaj, J Kumar, M Goyal, A Singh… - Journal of Pharmacology …, 2024 - ASPET
The classes of neuropharmaceuticals known as proteins and peptides serve as diagnostic
tools and are involved in specific communication in the peripheral and central nervous …

Brain delivery of peptides and proteins

C Dufès - Peptide and Protein Delivery, 2011 - Elsevier
Publisher Summary This chapter highlights the significant advances in brain delivery of
peptide and protein drugs made over the past three decades. While many limitations still …

Peptides as drug delivery vehicles across biological barriers

D Ghosh, X Peng, J Leal, RP Mohanty - Journal of pharmaceutical …, 2018 - Springer
Peptides are small biological molecules that are attractive in drug delivery and materials
engineering for applications including therapeutics, molecular building blocks and cell …

Peptide-based drug-delivery systems: A new hope for improving cancer therapy

AO Gonzalez-Cruz, J Hernandez-Juarez… - Journal of Drug Delivery …, 2022 - Elsevier
Abstract The usage of Peptide-Based Drug-delivery systems (PBDs) is a strategy in which
peptides carry a variety of compounds with pharmacological activity into cells. These …

The role of peptides in blood‐brain barrier nanotechnology

M Teixidó, E Giralt - Journal of Peptide Science: An Official …, 2008 - Wiley Online Library
The blood‐brain barrier (BBB) regulates the passage of molecules between the bloodstream
and the brain. Overcoming the difficulty of delivery drugs to specific areas of the brain is a …

Rational delivery strategies for the design of peptides with enhanced oral delivery

RT Borchardt - Drug development and industrial pharmacy, 1994 - Taylor & Francis
One of the most significant biological barriers to delivery of peptides and peptide mimetics is
the intestinal mucosa, which is a cell monolayer with tight intercellular junctions representing …

Peptide-based systems for drug delivery

DM Copolovici, AI Lupitu - Peptide Applications in Biomedicine …, 2018 - Elsevier
The modern life style and the increased life expectancy of the human population has led to
the necessity for treatments of a large and diverse number of diseases, including cancer …

Peptides as Pharmacological Carriers to the Brain: Promises, Shortcomings and Challenges

S Parrasia, I Szabò, M Zoratti… - Molecular …, 2022 - ACS Publications
Central nervous system (CNS) diseases are among the most difficult to treat, mainly
because the vast majority of the drugs fail to cross the blood-brain barrier (BBB) or to reach …

Peptide-based drug delivery systems

R Goyal, V Ramakrishnan - … and Biology of Nanomaterials for Drug Delivery, 2019 - Elsevier
Peptides are versatile biomolecules that function as signalling messengers, hormones,
carriers, and drugs. A variety of approaches are employed to engineer peptide-based …