Leptin, the protein product of the obese (ob) gene, has been suggested to play a role in the
regulation of food intake. As depressive episodes are frequently characterized by loss of …

OBJECTIVE Leptin, the product of the ob gene, is a recently discovered hormone secreted
by adipocytes. Serum leptin concentrations increase in correlation with the percentage of …

Objective Leptin, the obese gene product, is thought to regulate body fat through its action
on hypothalamic receptors that influence satiety. The hormonal regulation of leptin is …

Abstract Treatment with several psychopharmacological agents has been associated with
increased leptin plasma concentrations. We measured leptin plasma concentrations in 76 …

A decreased production of leptin has been reported in women with anorexia nervosa (AN)
and has been attributed merely to the patients' reduced body fat mass. The extent to which …

BACKGROUND: Appetite, food intake and weight are frequently altered in psychiatric
disorders such as major depression and schizophrenia. Leptin is an adipocyte hormone, as …

Objective: To review the literature regarding the role of leptin in psychiatric disorders.
Methods: A PubMed search was undertaken using the following keywords: leptin, psychosis …

Leptin, a peptide hormone secreted by adipocytes, plays a central role in controlling appetite
and weight in both rodents and humans. Basic science and clinical research suggest that …

Background Evidence for a role of leptin in depression is limited and conflicting.
Inconclusive findings may be explained by the complex effect of obesity on leptin signaling …

Leptin, a peptide hormone from adipose tissue and key player in weight regulation, has
been suggested to be involved in sleep and cognition and to exert antidepressant-like …