BACKGROUND Leptin is a peptide secreted by white adipose tissue which has been shown
to have a major influence on body weight regulation, while animal studies have revealed …

Leptin is thought to modulate feeding behaviour, body weight and energy metabolism by
acting through specific cellular receptors. Derangements of leptin production have been …

The aim of the present study was to evaluate serum leptin levels to demonstrate whether or
not its eventual alterations might have an etiopathogenetic significance in patients with …

Circulating leptin concentrations are known to be low in acute anorexia nervosa (AN), which
is characterized by low weight, amenorrhea and specific psychopathological features. In this …

A large number of diabetes patients suffer from major depression and are at high risk of
mortality. In view of a role of leptin in diabetes, depression and energy homeostasis, the …

Serum levels of leptin are decreased in underweight AN patients and increase with weight
restoration. To assess the relationship of decreased leptin levels with other hormonal …

The polypeptide leptin exerts a multitude of regulatory functions. It has been implicated in
the pathophysiology of inflammatory, metabolic and psychiatric disorders and has been …

Objective Animal models suggest that impaired leptin production, or leptin resistance
despite increased leptin levels, may contribute to depression. The link between leptin and …

Leptin, a hormone secreted from adipose tissue, was originally discovered to regulate body
weight. The localization of the leptin receptor in limbic structures suggests a potential role for …

Leptin, the product of the ob gene, is a recently discovered hormone secreted by adipocytes.
Cushing's syndrome is a disease state usually associated with weight gain due to the …