The involvement of leptin in humans revealed by mutations in leptin and leptin receptor genes

AD Strosberg, T Issad - Trends in pharmacological sciences, 1999 - cell.com
Current AWARENESS leptin in serum. Other mutations that do not affect secretion or do not
result in the loss of one or more epitopes might also exist; these would go undetected by …

Decreased serum leptin in bulimia nervosa

DC Jimerson, C Mantzoros, BE Wolfe… - The Journal of …, 2000 - academic.oup.com
The eating disorder bulimia nervosa has been associated with impaired satiety, decreased
resting metabolic rate, and abnormal neuroendocrine regulation. Preclinical studies suggest …

Relationship between plasma leptin levels and the tumor necrosis factor-α system in obese subjects

F Corica, A Allegra, A Corsonello, M Buemi… - International journal of …, 1999 - nature.com
OBJECTIVE: To evaluate the relationship between plasma leptin and the tumor necrosis
factor-α (TNFα), TNF receptor p60 (TNF-R1) and TNF receptor p80 (TNF-R2) concentrations …

Dexamethasone induces an acute and sustained rise in circulating leptin levels in normal human subjects

JP Miell, P Engloro, WF Blum - Hormone and Metabolic …, 1996 - thieme-connect.com
Leptin, the protein product of the ob gene, is thought to have a role in signalling satiety
through hypothalamic pathways. Glucocorticoids are potent stimulators of both ob gene …

Cerebrospinal fluid leptin in anorexia nervosa: correlation with nutritional status and potential role in resistance to weight gain

C Mantzoros, JS Flier, MD Lesem… - The Journal of …, 1997 - academic.oup.com
Studies in rodents have shown that leptin acts in the central nervous system to modulate
food intake and energy metabolism. To evaluate the possible role of leptin in the weight loss …

Serum leptin levels in women with anorexia nervosa

S Grinspoon, T Gulick, H Askari, M Landt… - The Journal of …, 1996 - academic.oup.com
Leptin is a protein encoded by the ob gene that is expressed in adipocytes and regulates
eating behavior via central neuroendocrine mechanisms. Serum leptin levels have been …

Reduced plasma leptin concentrations in bulimia nervosa

TD Brewerton, MD Lesem, A Kennedy… - …, 2000 - Elsevier
Leptin is a protein produced by the ob–ob gene which inhibits food intake. Plasma levels
have previously been reported to be altered in obesity and anorexia nervosa (AN) but not …

Serum leptin activity in obese and lean patients

M Friedman-Einat, L Camoin, Z Faltin, CI Rosenblum… - Regulatory …, 2003 - Elsevier
Blood levels of the satiety hormone leptin are directly correlated to fat stores in obese and
lean people. Therefore, leptin resistance is the logical explanation for the phenomenon of …

Influence of thyroid status on serum immunoreactive leptin levels

R Valcavi, M Zini, R Peino… - The journal of …, 1997 - academic.oup.com
Leptin, the product of the ob gene, is a recently discovered hormone secreted by adipocytes.
Serum leptin concentrations increase in correlation with the percentage of body fat, but …

The association of leptin secretion with cognitive performance in patients with eating disorders

C Wollenhaupt, L Wilke, Y Erim, M Rauh… - Psychiatry …, 2019 - Elsevier
This study is an investigation of neuropsychological performance in patients with anorexia
nervosa, bulimia nervosa, and binge eating disorder and hormonal secretion patterns for …