Storage of acetylcholine in synaptic vesicles plays a key role in maintaining cholinergic
function. Here we used mice with a targeted mutation in the vesicular acetylcholine …

An important step for cholinergic transmission involves the vesicular storage of acetylcholine
(ACh), a process mediated by the vesicular acetylcholine transporter (VAChT). In order to …

Defining the contribution of acetylcholine to specific behaviors has been challenging, mainly
because of the difficulty in generating suitable animal models of cholinergic dysfunction. We …

Cholinergic neurotransmission in the hippocampus is involved in cognitive functions,
including learning and memory. Strategies to enhance septohippocampal cholinergic …

Acetylcholine (ACh) is important for different cognitive functions such as learning, memory
and attention. The release of ACh depends on its vesicular loading by the vesicular …

The vesicular acetylcholine (ACh) transporter (VAChT) mediates ACh storage by synaptic
vesicles. However, the VAChT-independent release of ACh is believed to be important …

Acetylcholine, the first chemical to be identified as a neurotransmitter, is packed in synaptic
vesicles by the activity of VAChT (vesicular acetylcholine transporter). A decrease in VAChT …

Cholinergic neurotransmission depends upon the regulated release of acetylcholine. This
requires the loading of acetylcholine into synaptic vesicles by the vesicular acetylcholine …

J. Neurochem.(2010) 113, 943–951. Abstract Mammalian motor nerve terminals contain
hundreds of thousands of synaptic vesicles, but only a fraction of these vesicles is …

Acetylcholinergic (ACh) neurotransmission is essential for key organismal functions such as
locomotion and cognition. However, the mechanism through which ACh is regulated in the …