Rodents learn to associate the rewarding effects of drugs with the environment in which they
are encountered and, subsequently, will display a conditioned place preference (CPP) for …

Adolescence is a transitional period during development that is associated with a greater
likelihood of addiction to drugs than any other age. One possibility for this observation is that …

It has been speculated that an individual's response to novelty is a reliable predictor of its
vulnerability to develop addiction. However, the relationships between response to novelty …

In rodents, a conditioned place preference (CPP) can be induced by morphine. In the current
study, we designed a biased place conditioning paradigm to test the rewarding effects of …

The relationship between stress and drug use is well demonstrated. Stress-induced by
repeated social defeat (RSD) enhances the conditioned place preference (CPP) induced by …

We hypothesized that environmental enrichment in rats may reduce cocaine-seeking
behaviour elicited by cocaine-priming injections and by cocaine-associated cues. Rats …

Drug-using peers are recognized as a leading factor influencing drug use among
adolescents and young adults. One mechanism by which peers influence drug use is by …

Rationale Previous studies have shown that environmental context can powerfully modulate
the induction of psychomotor sensitization to cocaine in the rat. Rats that receive repeated …

The present protocol describes the Conditioned Place Preference (CPP) as a model of
relapse in drug addiction. In this model, animals are first trained to acquire a conditioned …

Rationale It has been demonstrated that major differences between mice of the C57BL/6J
and DBA/2J inbred strains for amphetamine-induced place conditioning (preference and …