Quest for Novel Preventive and Therapeutic Options Against Multidrug-Resistant Pseudomonas aeruginosa

S Irum, S Andleeb, A Ali, MI Rashid, M Majid - International Journal of …, 2021 - Springer
Pseudomonas aeruginosa (P. aeruginosa) is a critical healthcare challenge due to its ability
to cause persistent infections and the acquisition of antibiotic resistance mechanisms. Lack …

Prioritization of potential vaccine targets using comparative proteomics and designing of the chimeric multi-epitope vaccine against Pseudomonas aeruginosa

V Solanki, M Tiwari, V Tiwari - Scientific reports, 2019 - nature.com
Multidrug-resistant Pseudomonas aeruginosa is one of the worldwide health problems
involved in elevated mortality and morbidity. Therefore, it is important to find a therapeutic for …

Molecular Characterization and Designing of a Novel Multiepitope Vaccine Construct Against Pseudomonas aeruginosa

J Dey, SR Mahapatra, S Patnaik, S Lata… - International Journal of …, 2022 - Springer
Pseudomonas aeruginosa, an ESKAPE pathogen causes many fatal clinical diseases in
humans across the globe. Despite an increase in clinical instances of Pseudomonas …

Prediction of Potential Drug Targets and Vaccine Candidates Against Antibiotic-Resistant Pseudomonas aeruginosa

FS Shamsinejad, Z Zafari - International Journal of Peptide Research and …, 2022 - Springer
Pseudomonas aeruginosa is one of the leading causes of nosocomial infections,
characterized by increasing antibiotic resistance, severity and mortality. Therefore …

Integration of immunoinformatics and cheminformatics to design and evaluate a multitope vaccine against Klebsiella pneumoniae and Pseudomonas aeruginosa …

AM Gouda, MA Soltan, K Abd-Elghany… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction: Klebsiella pneumoniae (K. pneumoniae) and Pseudomonas aeruginosa (P.
aeruginosa) are the most common Gram-negative bacteria associated with pneumonia and …

In silico Identification of Novel Therapeutic Targets and Epitopes among the Essential Hypothetical Protein of Pseudomonas aeruginosa: A Novel Approach for …

B Atron, Z Yousif - 2023 - researchsquare.com
Background. Pseudomonas aeruginosa is a critical pathogen that represents a challenge in
healthcare due to its virulence and antibiotic resistance capabilities. The development of …

Subtractive proteomics to identify novel drug targets and reverse vaccinology for the development of chimeric vaccine against Acinetobacter baumannii

V Solanki, V Tiwari - Scientific reports, 2018 - nature.com
The emergence of drug-resistant Acinetobacter baumannii is the global health problem
associated with high mortality and morbidity. Therefore it is high time to find a suitable …

A Novel Design of Multi-epitope Peptide Vaccine Against Pseudomonas aeruginosa

F Esmaeilzadeh, S Mahmoodi - Letters in Drug Design & …, 2022 - ingentaconnect.com
Background: As an opportunistic pathogen, Pseudomonas aeruginosa causes many
different hazardous infections. The high mortality rate resulting from infection with this …

[HTML][HTML] Prediction of vaccine candidates against Pseudomonas aeruginosa: An integrated genomics and proteomics approach

MI Rashid, A Naz, A Ali, S Andleeb - Genomics, 2017 - Elsevier
Pseudomonas aeruginosa is among top critical nosocomial infectious agents due to its
persistent infections and tendency for acquiring drug resistance mechanisms. To date, there …

A computational approach to developing a multi-epitope vaccine for combating Pseudomonas aeruginosa–induced pneumonia and sepsis

SK Roy, MS Biswas, M Foyzur Raman… - Briefings in …, 2024 - academic.oup.com
Pseudomonas aeruginosa is a complex nosocomial infectious agent responsible for
numerous illnesses, with its growing resistance variations complicating treatment …