Catch me if you can: phagocytosis and killing avoidance by Cryptococcus neoformans

R Garcia-Rodas, O Zaragoza - FEMS Immunology & Medical …, 2012 - academic.oup.com
After inhalation of infectious particles, Cryptococcus neoformans resides in the alveolar
spaces, where it can survive and replicate in the extracellular environment. This yeast has …

[HTML][HTML] Cryptococcus neoformans: Tripping on Acid in the Phagolysosome

CM DeLeon-Rodriguez, A Casadevall - Frontiers in microbiology, 2016 - frontiersin.org
Cryptococcus neoformans (Cn) is a basidiomycetous pathogenic yeast that is a frequent
cause of meningoencephalitis in immunocompromised individuals. Cn is a facultative …

[HTML][HTML] Mechanisms of Cryptococcus neoformans-Mediated Host Damage

A Casadevall, C Coelho, A Alanio - Frontiers in immunology, 2018 - frontiersin.org
Cryptococcus neoformans is not usually considered a cytotoxic fungal pathogen but there is
considerable evidence that this microbe can damage host cells and tissues. In this essay …

Role of Phagocytosis in the Virulence of Cryptococcus neoformans

M Del Poeta - Eukaryotic cell, 2004 - Am Soc Microbiol
Phagocytosis is a receptor-mediated process that leads to the internalization of foreign
particles into phagocytic cells. Phagocytic cells, such as macrophages, dendritic cells, and …

The outcome of the Cryptococcus neoformans–macrophage interaction depends on phagolysosomal membrane integrity

D Leon-Rodriguez, M Carlos, DCP Rossi… - The Journal of …, 2018 - journals.aai.org
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. C. neoformans
resides within mature phagolysosomes where it often evades killing and replicates. C …

[HTML][HTML] Multiple Disguises for the Same Party: The Concepts of Morphogenesis and Phenotypic Variations in Cryptococcus neoformans

O Zaragoza - Frontiers in microbiology, 2011 - frontiersin.org
Although morphological transitions (such as hyphae and pseudohyphae formation) are a
common feature among fungi, the encapsulated pathogenic yeast Cryptococcus neoformans …

[HTML][HTML] Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophages

M Alvarez, A Casadevall - Current Biology, 2006 - cell.com
Cryptococcus neoformans (Cn) is an encapsulated yeast that is a facultative intracellular
pathogen and a frequent cause of human disease. The interaction of Cn with alveolar …

[HTML][HTML] The outcome of Cryptococcus neoformansintracellular pathogenesis in human monocytes

M Alvarez, T Burn, Y Luo, L Pirofski, A Casadevall - BMC microbiology, 2009 - Springer
Background Cryptococcus neoformans is an encapsulated yeast that is a facultative
intracellular pathogen. The interaction between macrophages and C. neoformans is critical …

Cryptococcus neoformans Is a Facultative Intracellular Pathogen in Murine Pulmonary Infection

M Feldmesser, Y Kress, P Novikoff… - Infection and …, 2000 - Am Soc Microbiol
To produce chronic infection, microbial pathogens must escape host immune defenses.
Infection with the human pathogenic fungus Cryptococcus neoformans is typically chronic …

[HTML][HTML] Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes

EA Gaylord, HL Choy, TL Doering - Pathogens, 2020 - mdpi.com
Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …