Background Uncontrolled inflammation is a typical feature of sepsis-related lung injury. The
key event in the progression of lung injury is Caspase-1-dependent alveolar macrophage …

Background Neutrophil extracellular traps (NETs) can cause acute lung injury (ALI)/acute
respiratory distress syndrome (ARDS) by inducing macrophage pyroptosis. The purpose of …

Background Uncontrollable inflammation is a critical feature of gram-negative bacterial
pneumonia-induced acute respiratory distress syndrome (ARDS). Both neutrophils and …

Previously, we demonstrated that neutrophil extracellular traps (NETs) play an essential role
in lipopolysaccharide (LPS)-induced acute lung injury. However, the underlying mechanism …

Neutrophil extracellular traps (NETs) assist pathogen clearance, while excessive NETs
formation is associated with exacerbated inflammatory responses and tissue injury in acute …

Sterile lung injury is an important clinical problem that complicates the course of severely ill
patients. Interruption of blood flow, namely ischemia–reperfusion (IR), initiates a sterile …

Background Acute respiratory distress syndrome (ARDS) is a neutrophil-associated disease.
Delayed neutrophil apoptosis and increased levels of neutrophil extracellular traps (NETs) …

Acute inflammation in response to both exogenous and endogenous danger signals can
lead to the assembly of cytoplasmic inflammasomes that stimulate the activation of caspase …

Neutrophil extracellular traps (NETs) production is a major strategy employed by
polymorphonuclear neutrophils (PMNs) to fight against microbes. NETs have been …

Background The present study was designed to explore the potential regulatory mechanism
between mitophagy and pyroptosis during sepsis-associated acute lung injury (ALI) …