Changes in DNA methylation in mouse lungs after a single intra-tracheal administration of nanomaterials

AM Tabish, K Poels, HM Byun, K Luyts, AA Baccarelli… - PloS one, 2017 - journals.plos.org
Aims This study aimed to investigate the effects of nanomaterial (NM) exposure on DNA
methylation. Methods and Results Intra-tracheal administration of NM: gold nanoparticles …

DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes

MI Sierra, L Rubio, GF Bayón, I Cobo… - …, 2017 - Taylor & Francis
Humans are increasingly exposed to nanoparticles and, although many of their
physiological effects have been described, the molecular mechanisms underlying them are …

Alterations in DNA methylation corresponding with lung inflammation and as a biomarker for disease development after MWCNT exposure

TA Brown, JW Lee, A Holian, V Porter… - …, 2016 - Taylor & Francis
Use of multi-walled carbon nanotubes (MWCNT) is growing which increases occupational
exposures to these materials. Their toxic potential makes it important to have an in-depth …

Multiwalled carbon nanotubes of varying size lead to DNA methylation changes that correspond to lung inflammation and injury in a mouse model

E Cole, JL Ray, S Bolten, RF Hamilton Jr… - Chemical Research …, 2019 - ACS Publications
Diversity in physicochemical properties of engineered multiwalled carbon nanotubes
(MWCNTs) increases the complexity involved in interpreting toxicity studies of these …

Low-dose carbon-based nanoparticle-induced effects in A549 lung cells determined by biospectroscopy are associated with increases in genomic methylation

J Li, M Tian, L Cui, J Dwyer, NJ Fullwood, H Shen… - Scientific reports, 2016 - nature.com
Nanotechnology has introduced many manufactured carbon-based nanoparticles (CNPs)
into our environment, generating a debate into their risks and benefits. Numerous …

Different effects of titanium dioxide nanoparticles instillation in young and adult mice on DNA methylation related with lung inflammation and fibrosis

Y Ma, Y Guo, H Ye, K Huang, Z Lv, Y Ke - Ecotoxicology and Environmental …, 2019 - Elsevier
Wide use of titanium dioxide nanoparticles (TiO 2 NPs) as white pigments induces
unintentionally release in environment which increases concerns about their adverse health …

The effect of nanomaterials on DNA methylation: A review

A Valente, L Vieira, MJ Silva, C Ventura - Nanomaterials, 2023 - mdpi.com
DNA methylation is an epigenetic mechanism that involves the addition of a methyl group to
a cytosine residue in CpG dinucleotides, which are particularly abundant in gene promoter …

In vivo epigenetic effects induced by engineered nanomaterials: A case study of copper oxide and laser printer-emitted engineered nanoparticles

X Lu, IR Miousse, SV Pirela, JK Moore, S Melnyk… - …, 2016 - Taylor & Francis
Evidence continues to grow on potential environmental health hazards associated with
engineered nanomaterials (ENMs). While the geno-and cytotoxic effects of ENMs have been …

Epigenetic modulation upon exposure of lung fibroblasts to TiO2 and ZnO nanoparticles: alterations in DNA methylation

NA Patil, WN Gade, DD Deobagkar - International journal of …, 2016 - Taylor & Francis
Titanium dioxide (TiO2) and zinc oxide (ZnO) nanoparticles (NPs) are promising candidates
for numerous applications in consumer products. This will lead to increased human …

Differences in MWCNT-and SWCNT-induced DNA methylation alterations in association with the nuclear deposition

D Öner, M Ghosh, H Bové, M Moisse, B Boeckx… - Particle and fibre …, 2018 - Springer
Background Subtle DNA methylation alterations mediated by carbon nanotubes (CNTs)
exposure might contribute to pathogenesis and disease susceptibility. It is known that both …