Elution pattern following agarose gel filtration of a fibrinogen solution before and after
freezing. position, determined in separate experiments, of the plasmin resistant fragments D …

The first demonstration that fibrinogen could be fragmented to molecular entities with
dissimilar physicochemical characteristics was provided by the work of Garner and Tillett …

The first attempt to chromatograph fibrinogen was made by Brandenberger (1954). He used
a column of untreated cellulose and found that fibrinogen was selectively retained at low …

Normal human plasma containing approximately 2.5 mg of fibrinogen per ml, 131 l-labelled
fibrinogen (less than 0.1 mg per ml) and 125 l-labelled fibrin monomer (between 0.01 and …

A qualitatively abnormal fibrinogen was detected in the plasma of a 53 year old woman with
severe arterial thrombotic disease. The concentrations of plasma fibrinogen and serum …

A method was described for the preparation of fibrinogen with 98% thrombin clottable
protein before, and 94% clottable protein after lyophilization. The fibrinogen was precipitated …

Polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate was
employed to compare various minor fibrinogen fractions of normal human plasma with …

The behaviour of labelled des‐AB fibrin in plasma was studied by gel filtration after it had
been injected into rabbits. Purified rabbit [125I] des‐AB fibrin was prepared by clotting of …

Early attempts to define the character of fibrinogen fragments in serum used
immunoelectrophoretic techniques (Fisher et af, 1967), and these established the similarity …

FIBRINOLYTIC activity arising in vivo is notoriously difficult to demonstrate. Even when it
seems obvious that there has been fibrinolysis in vivo, serum taken from the patient may fail …