Cell-based assays that predict in vivo neurotoxicity of urban ambient nano-sized particulate matter
Exposure to urban ambient particulate matter (PM) is associated with risk of Alzheimer's
disease and accelerated cognitive decline in normal aging. Assessment of the neurotoxic …
disease and accelerated cognitive decline in normal aging. Assessment of the neurotoxic …
Human brain derived cells respond in a type-specific manner after exposure to urban particulate matter (PM)
A Campbell, N Daher, P Solaimani, K Mendoza… - Toxicology in vitro, 2014 - Elsevier
Exposure to particulate matter (PM), a component of urban air pollution, may cause adverse
effects in the brain. Although the exact mechanisms involved are unknown, both oxidative …
effects in the brain. Although the exact mechanisms involved are unknown, both oxidative …
The adverse effects of air pollution on the nervous system
Exposure to ambient air pollution is a serious and common public health concern associated
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …
Microglial activation and inflammation caused by traffic-related particulate matter
KJ Bai, KJ Chuang, CL Chen, MK Jhan… - Chemico-biological …, 2019 - Elsevier
Neurotoxicity caused by particulate matter (PM) has been highlighted as being a potential
risk factor for neurodegenerative diseases. However, the effects of brain inflammation in …
risk factor for neurodegenerative diseases. However, the effects of brain inflammation in …
Role of brain extracellular vesicles in air pollution-related cognitive impairment and neurodegeneration
S Nicholson, A Baccarelli, D Prada - Environmental research, 2022 - Elsevier
A relationship between environmental exposure to air pollution and cognitive impairment
and neurological disorders has been described. Previous literature has focused on the …
and neurological disorders has been described. Previous literature has focused on the …
[HTML][HTML] Systemic exposure to air pollution induces oxidative stress and inflammation in mouse brain, contributing to neurodegeneration onset
C Milani, F Farina, L Botto, L Massimino… - International journal of …, 2020 - mdpi.com
In northern Italy, biomass burning-derived (BB) particles and diesel exhaust particles (DEP)
are considered the most significant contributors to ultrafine particle (UFP) emission …
are considered the most significant contributors to ultrafine particle (UFP) emission …
[HTML][HTML] Subacute inhalation of ultrafine particulate matter triggers inflammation without altering amyloid beta load in 5xFAD mice
Epidemiological studies reveal that air pollution exposure may exacerbate
neurodegeneration. Ultrafine particles (UFPs) are pollutants that remain unregulated in …
neurodegeneration. Ultrafine particles (UFPs) are pollutants that remain unregulated in …
[HTML][HTML] Ambient air pollution increases the risk of cerebrovascular and neuropsychiatric disorders through induction of inflammation and oxidative stress
Exposure to ambient air pollution is a well-established determinant of health and disease.
The Lancet Commission on pollution and health concludes that air pollution is the leading …
The Lancet Commission on pollution and health concludes that air pollution is the leading …
[HTML][HTML] Nanoparticulate matter exposure results in white matter damage and an inflammatory microglial response in an experimental murine model
M Connor, K Lamorie-Foote, Q Liu, K Shkirkova… - Plos one, 2021 - journals.plos.org
Exposure to ambient air pollution has been associated with white matter damage and
neurocognitive decline. However, the mechanisms of this injury are not well understood and …
neurocognitive decline. However, the mechanisms of this injury are not well understood and …
Effects of concentrated ambient ultrafine particulate matter on hallmarks of Alzheimer's disease in the 3xTgAD mouse model
D Herr, K Jew, C Wong, A Kennell, R Gelein… - Neurotoxicology, 2021 - Elsevier
Background Exposure to air pollution has been identified as a possible environmental
contributor to Alzheimer's Disease (AD) risk. As the number of people with AD worldwide …
contributor to Alzheimer's Disease (AD) risk. As the number of people with AD worldwide …