Cell-based assays that predict in vivo neurotoxicity of urban ambient nano-sized particulate matter

H Zhang, A Haghani, AH Mousavi, M Cacciottolo… - Free Radical Biology …, 2019 - Elsevier
Exposure to urban ambient particulate matter (PM) is associated with risk of Alzheimer's
disease and accelerated cognitive decline in normal aging. Assessment of the neurotoxic …

Human brain derived cells respond in a type-specific manner after exposure to urban particulate matter (PM)

A Campbell, N Daher, P Solaimani, K Mendoza… - Toxicology in vitro, 2014 - Elsevier
Exposure to particulate matter (PM), a component of urban air pollution, may cause adverse
effects in the brain. Although the exact mechanisms involved are unknown, both oxidative …

The adverse effects of air pollution on the nervous system

S Genc, Z Zadeoglulari, SH Fuss… - Journal of toxicology, 2012 - Wiley Online Library
Exposure to ambient air pollution is a serious and common public health concern associated
with growing morbidity and mortality worldwide. In the last decades, the adverse effects of air …

Microglial activation and inflammation caused by traffic-related particulate matter

KJ Bai, KJ Chuang, CL Chen, MK Jhan… - Chemico-biological …, 2019 - Elsevier
Neurotoxicity caused by particulate matter (PM) has been highlighted as being a potential
risk factor for neurodegenerative diseases. However, the effects of brain inflammation in …

Role of brain extracellular vesicles in air pollution-related cognitive impairment and neurodegeneration

S Nicholson, A Baccarelli, D Prada - Environmental research, 2022 - Elsevier
A relationship between environmental exposure to air pollution and cognitive impairment
and neurological disorders has been described. Previous literature has focused on the …

[HTML][HTML] Systemic exposure to air pollution induces oxidative stress and inflammation in mouse brain, contributing to neurodegeneration onset

C Milani, F Farina, L Botto, L Massimino… - International journal of …, 2020 - mdpi.com
In northern Italy, biomass burning-derived (BB) particles and diesel exhaust particles (DEP)
are considered the most significant contributors to ultrafine particle (UFP) emission …

[HTML][HTML] Subacute inhalation of ultrafine particulate matter triggers inflammation without altering amyloid beta load in 5xFAD mice

L Saveleva, P Vartiainen, V Górová, S Chew, I Belaya… - Neurotoxicology, 2022 - Elsevier
Epidemiological studies reveal that air pollution exposure may exacerbate
neurodegeneration. Ultrafine particles (UFPs) are pollutants that remain unregulated in …

[HTML][HTML] Ambient air pollution increases the risk of cerebrovascular and neuropsychiatric disorders through induction of inflammation and oxidative stress

O Hahad, J Lelieveld, F Birklein, K Lieb… - International journal of …, 2020 - mdpi.com
Exposure to ambient air pollution is a well-established determinant of health and disease.
The Lancet Commission on pollution and health concludes that air pollution is the leading …

[HTML][HTML] Nanoparticulate matter exposure results in white matter damage and an inflammatory microglial response in an experimental murine model

M Connor, K Lamorie-Foote, Q Liu, K Shkirkova… - Plos one, 2021 - journals.plos.org
Exposure to ambient air pollution has been associated with white matter damage and
neurocognitive decline. However, the mechanisms of this injury are not well understood and …

Effects of concentrated ambient ultrafine particulate matter on hallmarks of Alzheimer's disease in the 3xTgAD mouse model

D Herr, K Jew, C Wong, A Kennell, R Gelein… - Neurotoxicology, 2021 - Elsevier
Background Exposure to air pollution has been identified as a possible environmental
contributor to Alzheimer's Disease (AD) risk. As the number of people with AD worldwide …