Particulate matter and ultrafine particles in urban air pollution and their effect on the nervous system

JA Flood-Garibay, A Angulo-Molina… - … Science: Processes & …, 2023 - pubs.rsc.org
According to the World Health Organization, both indoor and urban air pollution are
responsible for the deaths of around 3.5 million people annually. During the last few …

[HTML][HTML] Rapid doubling of Alzheimer's amyloid-β40 and 42 levels in brains of mice exposed to a nickel nanoparticle model of air pollution

SH Kim, EM Knight, EL Saunders, AK Cuevas… - …, 2012 - ncbi.nlm.nih.gov
Background: Over 20 genetic risk factors have been confirmed to associate with elevated
risk for Alzheimer's disease (AD), but the identification of environmental and/or acquired risk …

[HTML][HTML] A pilot study to assess effects of long-term inhalation of airborne particulate matter on early Alzheimer-like changes in the mouse brain

DP Bhatt, KL Puig, MW Gorr, LE Wold, CK Combs - PLoS One, 2015 - journals.plos.org
Exposure to air pollutants, including particulate matter, results in activation of the brain
inflammatory response and Alzheimer disease (AD)-like pathology in dogs and humans …

[HTML][HTML] Effect of carbon nanomaterial dimension on the functional activity and degeneration of neurons

H Lee, S Kim, KS Hwang, NR Lim, HB Oh, IJ Cho… - Biomaterials, 2021 - Elsevier
Despite growing concerns regarding the threat of airborne nanoparticle-mediated brain
degeneration, the underlying pathological mechanisms remain unclear. Carbon …

[HTML][HTML] White matter pathology in alzheimer's transgenic mice with chronic exposure to low-level ambient fine particulate matter

TF Chen, SH Lee, WR Zheng, CC Hsu, KH Cho… - Particle and Fibre …, 2022 - Springer
Background Air pollution, especially fine particulate matter (PM), can cause brain damage,
cognitive decline, and an increased risk of neurodegenerative disease, especially …

Airborne fine particulate matter induces cognitive and emotional disorders in offspring mice exposed during pregnancy

C Zhao, P Xie, T Yong, W Huang, J Liu, D Wu, F Ji, M Li… - Science Bulletin, 2021 - Elsevier
Gestational exposure to PM 2.5 is associated with adverse postnatal outcomes. PM 2.5 can
enter alveoli by using intratracheal instillation, even penetrate through lung cells into the …

The role of reactive astrocytes in neurotoxicity induced by ultrafine particulate matter

B Li, X Chang, X Liang, T Liu, Y Shen, Q Zhang… - Science of The Total …, 2023 - Elsevier
Epidemiological studies have shown that ambient fine particulate matter (PM) can cause
various neurodegenerative diseases, including Alzheimer's disease. Reactive astrocytes are …

Exposure to nanoscale diesel exhaust particles: Oxidative stress, neuroinflammation, anxiety and depression on adult male mice

M Ehsanifar, AA Tameh, M Farzadkia… - Ecotoxicology and …, 2019 - Elsevier
Exposure to nanoscale diesel engines exhausted particles (DEPs) is a well-recognized risk
factor for respiratory and cardiovascular diseases. Rodents as commonly used models for …

Learning and memory disorders related to hippocampal inflammation following exposure to air pollution

M Ehsanifar, AJ Jafari, Z Montazeri… - … of Environmental Health …, 2021 - Springer
It has been demonstrated that sub-chronic exposure to air pollution containing nanoscale (˂
100 nm) diesel exhaust particles (DEPs) may lead to excessive oxidative stress and neuro …

Neurotoxicants Are in the Air: Convergence of Human, Animal, and In Vitro Studies on the Effects of Air Pollution on the Brain

LG Costa, TB Cole, J Coburn, YC Chang… - BioMed research …, 2014 - Wiley Online Library
In addition to increased morbidity and mortality caused by respiratory and cardiovascular
diseases, air pollution may also negatively affect the brain and contribute to central nervous …