Discussion This case highlights that intrathecal clonidine may diminish the ability to maintain
blood pressure during periods of hemodynamic lability. In our case this detrimental …

Background Clonidine, an alpha 2 agonist, is known to prolong the action of local
anesthetics, and to provide a satisfactory analgesia; hypotension and bradycardia have …

We evaluated the vasomotor effects of clonidine in awake subjects with an intact central
cardiovascular regulatory system. To determine the lower limit of the vasoconstrictive effect …

A patient with essential hypertension treated with clonidine developed accelerated acute
clonidine withdrawal syndrome during coronary artery bypass surgery. There were recurring …

IMPLICATIONS: In elderly patients after surgical repair of traumatic hip fracture, intrathecal
hyperbaric clonidine reduces hemodynamic side effects but also the quality and duration of …

Discussion Clonidine is not available for parenteral administration. Therefore, the
perioperative period is the time when withdrawal is most likely, due to the usual practice of …

We have studied the effect of clonidine pretreatment on cardiovascular responses to various
stimuli during craniotomy. Fifty-eight patients (ASA Class I–II), scheduled for supratentorial …

To the Editor: Clonidine was proposed to blunt circulatory breakthrough in patients
presenting for aortocoronary bypass. We would like to report the results of a pilot study of its …

The present study was conducted to examine the haemodynamic and endocrine effects of
clonidine, given as sole preanaesthetic medication, in neurosurgical patients. Nineteen …

In a double-blind, randomized, placebo-controlled study, 41 patients received clonidine 3
micrograms kg-1 or placebo at induction of isoflurane and nitrous oxide in oxygen …