The pulsatility of GnRH release is essential for reproductive function. The key events in
reproductive function, such as puberty onset and ovulatory cycles, are regulated by the …

The gonadotropin-releasing hormone (GnRH) neurons in the hypothalamus represent the
final common output in the central control of reproduction. GnRH secretion is modulated …

Uncovering the central mechanism underlying mammalian reproduction is warranted to
develop new therapeutic approaches for reproductive disorders in humans and domestic …

We tested the hypothesis that kisspeptin cells constitute the “pulse generator” for GnRH
secretion. In ewes, we determined whether iv administered kisspeptin elicits a secretory …

Work over the last 15 years on the control of pulsatile LH secretion has focused largely on a
set of neurons in the arcuate nucleus (ARC) that contains two stimulatory neuropeptides …

Accumulating findings during the past decades have demonstrated that the hypothalamic
arcuate kisspeptin neurons are supposed to be responsible for pulsatile release of …

In sheep and goats, the primer pheromone produced by the male induces out‐of‐seasonal
ovulation in anoestrous females, the so‐called 'male effect.'Because the initial endocrine …

Secretion of pulsatile gonadotropin-releasing hormone (GnRH) is essential for reproduction.
Kisspeptin neurons in the arcuate nucleus (ARC), which coexpress neurokinin B (NKB) and …

Pulsatile release of gonadotropin-releasing hormone (GnRH) is key to fertility. Pulse
frequency is modulated by gonadal steroids and likely arises subsequent to coordination of …

Exposure of females to a male pheromone accelerates pulsatile gonadotropin-releasing
hormone (GnRH) secretion in goats. Recent evidence has suggested that neurons in the …