The role of nitric oxide (NO•) as a mediator of cancer phenotype has led researchers to
investigate strategies for manipulating in vivo production and exogenous delivery of this …

Nitric oxide (NO) is a pleiotropic molecule critical to a number of physiological and
pathological processes. The last decade has witnessed major advances in dissecting NO …

Nitric oxide (NO) is a ubiquitous gas with free radical groups that is soluble in water, and
which is involved in numerous physiological functions including inflammatory and immune …

Much research over the past two decades has focussed on understanding the complex
interactions of nitric oxide (NO) in both physiological and pathological processes. As with …

A blueprint for the ideal anticancer molecule would include most of the properties of nitric
oxide (NO•), but the ability to exploit these characteristics in a therapeutic setting requires a …

Despite the improved understanding of nitric oxide (NO) biology and the large amount of
preclinical experiments testing its role in cancer development and progression, it is still …

Purpose The diatomic radical nitric oxide (NO) has been the cause of intense debate with
implication in carcinogenesis, tumour progression, invasion, angiogenesis and modulation …

The mechanistic roles of nitric oxide (NO) during cancer progression have been important
considerations since its discovery as an endogenously generated free radical. Nonetheless …

Nitric oxide (NO) is a signaling molecule with pleiotropic physiological roles in normal cells
and pathophysiological roles in cancer. NO synthetase expression and NO synthesis are …

Nitric oxide is a key second messenger in most tissues, where it is generated at low
concentrations, predominantly by the catalytic action of two constitutively expressed isoforms …