Plasmodium falciparum gametocyte dynamics in areas of different malaria endemicity

K Stepniewska, RN Price, CJ Sutherland, CJ Drakeley… - Malaria journal, 2008 - Springer
Background The aim of this study was to identify and compare factors associated with
Plasmodium falciparum gametocyte carriage in three regions of differing malaria endemicity …

Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of …

T Bousema, L Okell, S Shekalaghe, JT Griffin, S Omar… - Malaria journal, 2010 - Springer
Background There is renewed acknowledgement that targeting gametocytes is essential for
malaria control and elimination efforts. Simple mathematical models were fitted to data from …

Demographical, hematological and serological risk factors for Plasmodium falciparum gametocyte carriage in a high stable transmission zone in Cameroon

E Essangui, CE Eboumbou Moukoko, N Nguedia… - PLoS …, 2019 - journals.plos.org
Presence of mature gametocyte forms of malaria parasites in peripheral blood is a key
requirement for malaria transmission. Yet, studies conducted in most malaria transmission …

Risk Factors for Plasmodium falciparum Gametocyte Positivity in a Longitudinal Cohort

L Grange, C Loucoubar, O Telle, A Tall, J Faye… - PLoS …, 2015 - journals.plos.org
Malaria transmission intensity is highly heterogeneous even at a very small scale.
Implementing targeted intervention in malaria transmission hotspots offers the potential to …

Increased investment in gametocytes in asymptomatic Plasmodium falciparum infections in the wet season

CO Oduma, S Ogolla, H Atieli, BN Ondigo… - BMC infectious …, 2021 - Springer
Background Transmission stemming from asymptomatic infections is increasingly being
recognized as a threat to malaria elimination. In many regions, malaria transmission is …

Gametocytaemia after drug treatment of asymptomatic Plasmodium falciparum

S Dunyo, P Milligan, T Edwards, C Sutherland… - PLoS clinical …, 2006 - journals.plos.org
Objectives Treatment of Plasmodium falciparum malaria with sulfadoxine-pyrimethamine
(SP) is followed by a sharp rise in the prevalence and density of gametocytes. We did a …

Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta …

WWARN Gametocyte Study Group teun. bousema … - BMC medicine, 2016 - Springer
Background Gametocytes are responsible for transmission of malaria from human to
mosquito. Artemisinin combination therapy (ACT) reduces post-treatment gametocyte …

The plasticity of Plasmodium falciparum gametocytaemia in relation to age in Burkina Faso

AL Ouédraogo, T Bousema, SJ de Vlas… - Malaria journal, 2010 - Springer
Background Malaria transmission depends on the presence of gametocytes in the
peripheral blood. In this study, the age-dependency of gametocytaemia was examined by …

(Sub) microscopic Plasmodium falciparum gametocytaemia in Kenyan children after treatment with sulphadoxine-pyrimethamine monotherapy or in combination with …

P Schneider, T Bousema, S Omar, L Gouagna… - International journal for …, 2006 - Elsevier
The effects of drugs on Plasmodium falciparum transmission stages may reduce the spread
of parasites in the population and contribute to malaria control. Detailed quantitative studies …

A randomized feasibility trial comparing four antimalarial drug regimens to induce Plasmodium falciparum gametocytemia in the controlled human malaria infection …

IJ Reuling, LA Van De Schans, LE Coffeng, K Lanke… - Elife, 2018 - elifesciences.org
Background: Malaria elimination strategies require a thorough understanding of parasite
transmission from human to mosquito. A clinical model to induce gametocytes to understand …