Factors associated with predisposition and vulnerability to neurodegenerative disorders may
be described usefully within the context of gene-environment interplay. There are many …

The understanding of how environmental exposures interact with genetics in central nervous
system dysfunction has gained great momentum in the last decade. Seminal findings have …

Neurodegenerative diseases are a heterogeneous group of pathologies which includes
complex multifactorial diseases, monogenic disorders and disorders for which inherited …

Neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD),
Amyotrophic lateral sclerosis (ALS) and retinal degeneration have been studied extensively …

Non-cancer degenerative diseases are a complex and heterogeneous mix of different
diseases sharing a complex and long-lasting pathogenesis resulting in irreversible cell loss …

Evidence implicates environmental factors in the pathogenesis of diverse complex
neurodevelopmental disorders. However, the identity of specific environmental chemicals …

Neurodevelopmental disorders (NDDs) include a huge variety of pathologies characterised
by varying degrees of intellectual disability and behavioural dysfunction. Research during …

The vast majority of disease is due to complex relationships between genetic and
environmental factors. Single genetic or environmental causes are rare. Unfortunately, this …

Interplay between genetic and environmental factors during critical time windows can have
effects that span from neurodevelopment to neurodegeneration. We present the concept of …

The classification of neurodegenerative disorders includes human diseases that vary
significantly in terms of their incidence, clinical presentation, and prognosis. All of these …