[HTML][HTML] GSK3β and ERK regulate the expression of 78 kDa SG2NA and ectopic modulation of its level affects phases of cell cycle
Striatin and SG2NA are essential constituents of the multi-protein STRIPAK assembly
harbouring protein phosphatase PP2A and several kinases. SG2NA has several isoforms …
harbouring protein phosphatase PP2A and several kinases. SG2NA has several isoforms …
Subcellular dynamics of variants of SG2NA in NIH3T3 fibroblasts
Abstract SG2NA, a WD40 repeat protein of the Striatin subfamily, has four splicing and one
messenger RNA edit variants. It is fast emerging as a scaffold for multimeric signaling …
messenger RNA edit variants. It is fast emerging as a scaffold for multimeric signaling …
[HTML][HTML] SG2NA is a regulator of endoplasmic reticulum (ER) homeostasis as its depletion leads to ER stress
SG2NA belongs to a three-member striatin subfamily of WD40 repeat superfamily of
proteins. It has multiple protein-protein interaction domains involved in assembling …
proteins. It has multiple protein-protein interaction domains involved in assembling …
Ectopic expression of 35 kDa and knocking down of 78 kDa SG2NAs induce cytoskeletal reorganization, alter membrane sialylation, and modulate the markers of EMT
SG2NA is a protein of the striatin family that organizes STRIPAK complexes. It has splice
variants expressing differentially in tissues. Its 78 kDa isoform regulates cell cycle, maintains …
variants expressing differentially in tissues. Its 78 kDa isoform regulates cell cycle, maintains …
Tissue specific expression of SG2NA is regulated by differential splicing, RNA editing and differential polyadenylation
SG2NA belongs to a three member Striatin subfamily of WD-40 repeat superfamily. It has
multiple protein–protein interaction domains that are involved in the assembly of supra …
multiple protein–protein interaction domains that are involved in the assembly of supra …
Regulation of protein stability by GSK3 mediated phosphorylation
Glycogen synthase kinase-3 (GSK3) plays important roles in numerous signaling pathways
that regulate a variety of cellular processes including cell proliferation, differentiation …
that regulate a variety of cellular processes including cell proliferation, differentiation …
Mitogenic Signaling by the gep Oncogene Involves the Upregulation of S-Phase Kinase-Associated Protein 2
R Radhakrishnan, JH Ha… - Genes & …, 2010 - journals.sagepub.com
The gep oncogene, defined by the activated mutant of the α-subunit of the G protein G12
(Gα12Q229L or Gα12QL), potently stimulates the proliferation of many different cell types in …
(Gα12Q229L or Gα12QL), potently stimulates the proliferation of many different cell types in …
GSK-3: An “Ace” Among Kinases
TL Mathuram - Cancer Biotherapy & Radiopharmaceuticals, 2024 - liebertpub.com
Background: Glycogen synthase kinase-3 (GSK-3) is a serine/threonine kinase known to be
participating in the regulation of β-catenin signaling (Wnt signaling). They help in the …
participating in the regulation of β-catenin signaling (Wnt signaling). They help in the …
[HTML][HTML] Molecular modeling and molecular dynamics simulations based structural analysis of the SG2NA protein variants
Background SG2NA is a member of the striatin sub-family of WD-40 repeat proteins. Striatin
family members have been associated with diverse physiological functions. SG2NA has also …
family members have been associated with diverse physiological functions. SG2NA has also …
[HTML][HTML] Novel non-phosphorylated serine 9/21 GSK3β/α antibodies: expanding the tools for studying GSK3 regulation
T Grabinski, NM Kanaan - Frontiers in molecular neuroscience, 2016 - frontiersin.org
Glycogen synthase kinase 3 (GSK3) β and α are serine/threonine kinases involved in many
biological processes. A primary mechanism of GSK3 activity regulation is phosphorylation of …
biological processes. A primary mechanism of GSK3 activity regulation is phosphorylation of …