Near-Infrared Light Photocontrolled Targeting, Bioimaging, and Chemotherapy with Caged Upconversion Nanoparticles in Vitro and in Vivo

YH Chien, YL Chou, SW Wang, ST Hung, MC Liau… - Acs Nano, 2013 - ACS Publications
The major challenge in current chemotherapy is to increase local effective therapeutic
concentration of drugs as well as to minimize toxicity and side effects for patients. The …

Near-infrared light activated delivery platform for cancer therapy

M Lin, Y Gao, F Hornicek, F Xu, TJ Lu, M Amiji… - Advances in colloid and …, 2015 - Elsevier
Cancer treatment using conventional drug delivery platforms may lead to fatal damage to
normal cells. Among various intelligent delivery platforms, photoresponsive delivery …

Near-infrared-triggered anticancer drug release from upconverting nanoparticles

LL Fedoryshin, AJ Tavares, E Petryayeva… - … applied materials & …, 2014 - ACS Publications
Targeted drug delivery using functional nanoparticles has provided new strategies for
improving therapeutic efficacy while concurrently minimizing toxicity. Photodynamic therapy …

Assembly of upconversion nanophotosensitizer in vivo to achieve scatheless real-time imaging and selective photodynamic therapy

Y Feng, Y Wu, J Zuo, L Tu, I Que, Y Chang, LJ Cruz… - Biomaterials, 2019 - Elsevier
A perfect “off” to “on” switch of the therapeutic function is very important to minimize the
phototoxicity of nanoplatforms assisted imaging-guided photodynamic therapy (PDT) of …

Seeing, targeting and delivering with upconverting nanoparticles

G Jalani, V Tam, F Vetrone… - Journal of the American …, 2018 - ACS Publications
Efficient control over drug release is critical to increasing drug efficacy and avoiding side
effects. An ideal drug delivery system would deliver drugs in the right amount, at the right …

Near‐infrared photoregulated drug release in living tumor tissue via yolk‐shell upconversion nanocages

L Zhao, J Peng, Q Huang, C Li, M Chen… - Advanced Functional …, 2014 - Wiley Online Library
Phototrigger‐controlled drug‐release devices (PDDs) can be conveniently manipulated by
light to obtain on‐demand release patterns, thereby affording an improved therapeutic …

[HTML][HTML] Upconversion nanoparticles for photodynamic therapy and other cancer therapeutics

C Wang, L Cheng, Z Liu - Theranostics, 2013 - ncbi.nlm.nih.gov
Photodynamic therapy (PDT) is a non-invasive treatment modality for a variety of diseases
including cancer. PDT based on upconversion nanoparticles (UCNPs) has received much …

[HTML][HTML] Near-infrared-triggered upconverting nanoparticles for biomedicine applications

MK Mahata, R De, KT Lee - Biomedicines, 2021 - mdpi.com
Due to the unique properties of lanthanide-doped upconverting nanoparticles (UCNP) under
near-infrared (NIR) light, the last decade has shown a sharp progress in their biomedicine …

Near-infrared light induced in vivo photodynamic therapy of cancer based on upconversion nanoparticles

C Wang, H Tao, L Cheng, Z Liu - Biomaterials, 2011 - Elsevier
Upconversion nanoparticles (UCNPs) that emit high-energy photons upon excitation by the
low-energy near-infrared (NIR) light are emerging as new optical nano-probes useful in …

[HTML][HTML] Recent advances in functionalized upconversion nanoparticles for light-activated tumor therapy

H Chu, T Cao, G Dai, B Liu, H Duan, C Kong, N Tian… - RSC …, 2021 - pubs.rsc.org
Upconversion nanoparticles (UCNPs) are a class of optical nanocrystals doped with
lanthanide ions that offer great promise for applications in controllable tumor therapy. In …