Localization and steroid regulation of prostaglandin E2 receptor protein expression in ovine cervix

T Schmitz, BA Levine, PW Nathanielsz - Reproduction, 2006 - rep.bioscientifica.com
Although prostaglandin E 2 (PGE 2) has been identified as a central mediator of the cervical
ripening process, the mechanisms responsible for PGE 2 ripening are still poorly …

The mRNA expression of prostaglandin E receptors EP2 and EP4 and the changes in glycosaminoglycans in the sheep cervix during the estrous cycle

CM Kershaw-Young, M Khalid, MR McGowan… - Theriogenology, 2009 - Elsevier
Transcervical artificial insemination in sheep is limited by the inability to completely
penetrate the cervix with an inseminating pipette. Penetration is partially enhanced at estrus …

The effect of estradiol on COX-2, EP2, and EP4 mRNA expression and the extracellular matrix in the cervix of the hypogonadotrophic, ovariectomized ewe

CM Kershaw-Young, RJ Scaramuzzi, MR McGowan… - Theriogenology, 2010 - Elsevier
There is a degree of cervical relaxation in the ewe at estrus that is regulated by changes in
prostaglandin synthesis, prostaglandin receptor expression, and changes in the cervical …

Hormonal regulation of prostaglandin E2 receptors: localization and expression in rat cervical tissue

AC Hinton, PL Grigsby, BA Pitzer… - Reproductive …, 2010 - journals.sagepub.com
Prostaglandin E2 (PGE2) may regulate uterine activation and cervical ripening for labor
through specific contractile and relaxatory receptors (EP1-4). The aim of this study was to …

Sufficient progesterone-priming prior to estradiol stimulation is required for optimal induction of the cervical prostaglandin system in pregnant sheep at 0.7 gestations

WX Wu, T Coksaygan, K Chakrabarty… - Biology of …, 2005 - academic.oup.com
The purposes of this study were to determine the separate and interactive functions of
progesterone and estradiol in regulating the cervical prostaglandin (PG) system in pregnant …

Immunolocalization of adipocytes and prostaglandin E2 and its four receptor proteins EP1, EP2, EP3, and EP4 in the caprine cervix during spontaneous term labor

G Gu, Q Gao, X Yuan, L Huang, L Ge - Biology of reproduction, 2012 - academic.oup.com
The mechanisms of cervical ripening and dilation in mammals remain obscure. Information
is lacking about the localization of prostaglandin E2 (PGE2)-producing cells and PGE2 …

Regulation of the prostaglandin enzymatic system by estradiol and progesterone in nonpregnant sheep cervix

Q Zhang, V Collins, K Chakrabarty, JC Rose… - …, 2007 - rep.bioscientifica.com
In the present study, we examined the in vivo effects of estradiol (E 2) and progesterone on
cyclooxygenase (COX) 2, prostaglandin F synthase (PTGFS, also known as PGFS), and …

Molecular Cloning and Characterization of Bovine Prostaglandin E2 Receptors EP2 and EP4: Expression and Regulation in Endometrium and Myometrium during …

JA Arosh, SK Banu, P Chapdelaine, V Emond… - …, 2003 - academic.oup.com
Prostaglandins (PGs) play important functions in the reproductive system, and PGE2
appears necessary for recognition of pregnancy. We have found that PGE2 is able to …

Prostanoid receptors EP2, EP4, and FP are regulated by estradiol in bovine oviductal smooth muscle

N Huang, B Liu, Z Dong, W Mao, N Zhang, C Li… - Prostaglandins & other …, 2015 - Elsevier
Gamete and embryo transport is an important function of the oviduct. This transport involves
both smooth muscle contraction and epithelial cell secretions, the former of which is …

Regulation of bovine cervical secretion of prostaglandins and synthesis of cyclooxygenase by oxytocin

M Shemesh, L Dombrovski, M Gurevich… - Reproduction, fertility …, 1997 - CSIRO Publishing
Prostaglandin E2 (PGE2) can cause softening of the bovine cervix at oestrus when receptors
for oxytocin (OT) are maximally present, indicating a relationship between OT and PGE2 …