Characterization of prostaglandin E2 receptors (EP2, EP4) in the horse oviduct

BA Ball, KE Scoggin, MHT Troedsson… - Animal reproduction …, 2013 - Elsevier
Biological effects of prostaglandin E 2 are mediated via one of four receptors designated
EP1, EP2, EP3 and EP4 which are encoded by separate genes. In general, EP1 and EP3 …

Differential regulation of prostaglandin EP and FP receptors in pregnant sheep myometrium and endometrium during spontaneous term labor

XH Ma, WX Wu, PW Nathanielsz - Biology of reproduction, 1999 - academic.oup.com
In the present study, we characterized the mRNA abundance of prostaglandin E2 receptor
subtypes (EP1 and EP3, which stimulate excitatory responses; EP2 and EP4, which …

Temporal and tissue-specific expression of prostaglandin receptors EP2, EP3, EP4, FP, and cyclooxygenases 1 and 2 in uterus and fetal membranes during bovine …

JA Arosh, SK Banu, P Chapdelaine, MA Fortier - Endocrinology, 2004 - academic.oup.com
Uteroplacental prostaglandins (PGs) play pivotal roles in maintenance and/or termination of
pregnancy in mammals. Regulation of PG biosynthetic and signaling mechanisms in …

Identification and localization of prostaglandin E2 receptors in upper and lower segment human myometrium during pregnancy

S Astle, S Thornton, DM Slater - Molecular Human Reproduction, 2005 - academic.oup.com
Abstract Prostaglandin E2 (PGE2) plays a key role in the maintenance of human pregnancy
and labour onset. PGE2 can elicit diverse actions within the uterus depending on the PGE2 …

An in vitro investigation of the actions of reproductive hormones on the cervix of the ewe in the follicular stage: the effects of 17β-estradiol, oxytocin, FSH, and …

L Falchi, RJ Scaramuzzi - Theriogenology, 2015 - Elsevier
During the periovulatory period, the cervix of the ewe relaxes and this mechanism is thought
to be mediated by oxytocin and prostaglandin E 2 (PGE 2) in response to increased …

Expression and regulation of the rat prostaglandin E2 receptor type 4 (EP4) in pregnant cervical tissue

EK Chien, C MacGregor - American journal of obstetrics and gynecology, 2003 - Elsevier
OBJECTIVE: Prostaglandins play an important role in the regulation of parturition and
cervical ripening. Prostaglandin E2 (PGE2)–induced tissue remodeling is mediated through …

Effects of gestational age on prostaglandin EP receptor expression and functional involvement during in vitro contraction of the guinea pig uterus

KK Terry, WS Lebel, KA Riccardi, WA Grasser… - … and essential fatty acids, 2008 - Elsevier
Prostaglandin E2 (PGE2) exerts diverse biological effects through four G-protein-coupled
cell surface receptor subtypes, EP1–4. This study's objective was to characterize EP1–4 …

The expression of ERα, OTR, cPLA2, COX-2, and PPARγ in the cervix of the ewe during the estrous cycle

L Falchi, RJ Scaramuzzi - Theriogenology, 2013 - Elsevier
The ovine cervix relaxes at estrus allowing easier entry of spermatozoa into the uterus. The
mechanism responsible for this relaxation is not fully elucidated and we hypothesized that …

The expression of prostaglandin endoperoxide synthase 2 messenger RNA and the proportion of smooth muscle and collagen in the sheep cervix during the estrous …

CM Kershaw, RJ Scaramuzzi… - Biology of …, 2007 - academic.oup.com
The use of transcervical artificial insemination in sheep is limited because of the anatomy of
the cervix, which restricts the passage of an inseminating pipette into the uterine lumen …

Prostaglandin E2 Receptor Subtype EP2 Gene Expression in the Mouse Uterus Coincides with Differentiation of the Luminal Epithelium for Implantation

H Lim, SK Dey - Endocrinology, 1997 - academic.oup.com
Among the PGs, PGE2 is considered especially important for implantation and
decidualization. Four major PGE2 receptor subtypes, EP1, EP2, EP3, and EP4, mediate …