Roles of oxidants and redox signaling in the pathogenesis of acute respiratory distress syndrome

S Tasaka, F Amaya, S Hashimoto… - Antioxidants & redox …, 2008 - liebertpub.com
The acute respiratory distress syndrome (ARDS) is a disease process that is characterized
by diffuse inflammation in the lung parenchyma and resultant permeability edema. The …

Biological and physiological role of reactive oxygen species–the good, the bad and the ugly

L Zuo, T Zhou, BK Pannell, AC Ziegler… - Acta …, 2015 - Wiley Online Library
Reactive oxygen species (ROS) are chemically reactive molecules that are naturally
produced within biological systems. Research has focused extensively on revealing the …

Reactive oxygen species in chronic obstructive pulmonary disease

S Boukhenouna, MA Wilson, K Bahmed… - Oxidative medicine …, 2018 - Wiley Online Library
Chronic obstructive pulmonary disease (COPD) includes chronic bronchitis and
emphysema. Environmental exposure, primarily cigarette smoking, can cause high oxidative …

[HTML][HTML] Reactive oxygen species and antioxidative defense in chronic obstructive pulmonary disease

A Taniguchi, M Tsuge, N Miyahara, H Tsukahara - Antioxidants, 2021 - mdpi.com
The respiratory system is continuously exposed to endogenous and exogenous oxidants.
Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation of …

Oxidants/antioxidants and COPD

W MacNee - Chest, 2000 - Elsevier
Oxidative stress results from an oxidant/antioxidant imbalance, an excess of oxidants and/or
a depletion of antioxidants. Oxidative stress is thought to play an important role in the …

Oxidative stress in the lung–the essential paradox

LK Rogers, MJ Cismowski - Current opinion in toxicology, 2018 - Elsevier
As eukaryotic life evolved, so too did the need for a source of energy that meets the
requirements of complex organisms. Oxygen provides this vast potential energy source, but …

Oxidative stress in asthma and COPD: antioxidants as a therapeutic strategy

P Kirkham, I Rahman - Pharmacology & therapeutics, 2006 - Elsevier
Asthma and chronic obstructive pulmonary disease (COPD) are inflammatory lung diseases
that are characterized by systemic and chronic localized inflammation and oxidative stress …

[HTML][HTML] Oxidative stress and therapeutic development in lung diseases

L Villegas, T Stidham… - Journal of pulmonary & …, 2014 - ncbi.nlm.nih.gov
Oxidative stress has many implications in the pathogenesis of lung diseases. In this review,
we provide an overview of Reactive Oxygen Species (ROS) and nitrogen (RNS) species and …

[HTML][HTML] Oxidative stress and air pollution: its impact on chronic respiratory diseases

MP Sierra-Vargas, JM Montero-Vargas… - International Journal of …, 2023 - mdpi.com
Redox regulation participates in the control of various aspects of metabolism. Reactive
oxygen and nitrogen species participate in many reactions under physiological conditions …

Reactive oxygen species in cell signaling

VJ Thannickal, BL Fanburg - American Journal of …, 2000 - journals.physiology.org
Reactive oxygen species (ROS) are generated as by-products of cellular metabolism,
primarily in the mitochondria. When cellular production of ROS overwhelms its antioxidant …