Neuroinflammation in Parkinson's disease: from gene to clinic: a systematic review

C Castillo-Rangel, G Marin… - International Journal of …, 2023 - mdpi.com
Parkinson's disease is a neurodegenerative disease whose progression and clinical
characteristics have a close bidirectional and multilevel relationship with the process of …

The involvement of neuroinflammation in the onset and progression of Parkinson's disease

A Jurcau, FL Andronie-Cioara… - International Journal of …, 2023 - mdpi.com
Parkinson's disease is a neurodegenerative disease exhibiting the fastest growth in
incidence in recent years. As with most neurodegenerative diseases, the pathophysiology is …

Epigenetic regulation of neuroinflammation in Parkinson's disease

M Rasheed, J Liang, C Wang, Y Deng… - International Journal of …, 2021 - mdpi.com
Neuroinflammation is one of the most significant factors involved in the initiation and
progression of Parkinson's disease. PD is a neurodegenerative disorder with a motor …

Neurodegeneration and inflammation—an interesting interplay in Parkinson's disease

C Marogianni, M Sokratous, E Dardiotis… - International journal of …, 2020 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder, caused by, so far, unknown
pathogenetic mechanisms. There is no doubt that pro-inflammatory immune-mediated …

Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy

L Qian, PM Flood, JS Hong - Journal of neural transmission, 2010 - Springer
Parkinson's disease (PD) is a neurodegenerative movement disorder characterized by the
progressive loss of dopaminergic neurons in the substantia nigra and depletion of dopamine …

Pre-Clinical studies identifying molecular pathways of neuroinflammation in Parkinson's disease: a systematic review

M Fathi, K Vakili, S Yaghoobpoor… - Frontiers in Aging …, 2022 - frontiersin.org
Parkinson's disease (PD), the second most common neurodegenerative disorder, is
characterized by neuroinflammation, formation of Lewy bodies, and progressive loss of …

Neurodegeneration and neuroinflammation in Parkinson's disease: a self-sustained loop

G Arena, K Sharma, G Agyeah, R Krüger… - Current Neurology and …, 2022 - Springer
Abstract Purpose of Review Neuroinflammation plays a significant role in Parkinson's
disease (PD) etiology along with mitochondrial dysfunction and impaired proteostasis. In this …

Inflammatory mechanisms in Parkinson's disease: from pathogenesis to targeted therapies

SYH Lee, NJ Yates, SJ Tye - The Neuroscientist, 2022 - journals.sagepub.com
Inflammation is a critical factor contributing to the progressive neurodegenerative process
observed in Parkinson's disease (PD). Microglia, the immune cells of the central nervous …

Insights into neuroinflammation in Parkinson's disease: from biomarkers to anti‐inflammatory based therapies

NP Rocha, AS De Miranda… - BioMed research …, 2015 - Wiley Online Library
Parkinson's disease (PD) is the second most common neurodegenerative disorder
worldwide, being characterized by the progressive loss of dopaminergic neurons in the …

Neuroinflammation in Parkinson's disease and its potential as therapeutic target

Q Wang, Y Liu, J Zhou - Translational neurodegeneration, 2015 - Springer
Abstract Parkinson's disease (PD), the second most common age-associated
neurodegenerative disorder, is characterized by the loss of dopaminergic (DA) neurons and …