Fibrosis, or the accumulation of extracellular matrix molecules that make up scar tissue, is a
common result of chronic tissue injury. Advances in the clinical management of fibrotic …

Fibrosis, the progressive accumulation of connective tissue that occurs in response to injury,
causes irreparable organ damage and may result in organ failure. The few available …

Fibrosis plays an important role in many different pathologies. It results from tissue injury,
chronic inflammation, autoimmune reactions and genetic alterations, and it is characterized …

The discovery and development of biomarkers for fibrotic diseases have potential utility in
clinical decision-making as well as in pharmaceutical research and development. This …

Fibrosis, a complex process of abnormal tissue healing which inevitably leads to loss of
physiological organ structure and function, is a worldwide leading cause of death. Despite a …

Background Fibrosis, which is characterized by the pathological accumulation of collagen, is
recognized as an important feature of many chronic diseases, and as such, constitutes an …

An imbalance of extracellular matrix (ECM) deposition and turnover is a hallmark of fibrotic
pathologies as opposed to normal repair response to injury across several organs …

We describe a multiplexed imaging mass spectrometry approach especially suitable for
fibrosis research. Fibrosis is a process characterized by excessive extracellular matrix …

Current understanding of fibrosis remains incomplete despite the increasing burden of
related diseases. Preclinical models are used to dissect the pathogenesis and dynamics of …

Fibrosis is the formation or development of excess fibrous connective tissue (largely type I
collagen) in a tissue as a result of a reparative or reactive process. Fibrosis, or scarring, is a …