Intragastric administration of Pien Tze Huang enhanced wound healing in diabetes by inhibiting inflammation and improving energy generation

J Zhang, G Cao, L Tian, J Hou, Y Zhang, H Xu, M Wang… - Phytomedicine, 2023 - Elsevier
Background and purpose As a complex and challenging complication for the patients with
diabetes mellitus, diabetic ulcers are difficult to heal and current strategies cannot fulfill the …

[HTML][HTML] Pien-tze-huang promotes wound healing in streptozotocin-induced diabetes models associated with improving oxidative stress via the Nrf2/ARE pathway

Y Liu, J Mo, F Liang, S Jiang, J Xiong… - Frontiers in …, 2023 - frontiersin.org
Diabetic foot ulcers are a serious complication of diabetes, with high mortality and a lack of
effective clinical treatment, which leads to a considerable financial burden. Pien-Tze-Huang …

[HTML][HTML] Integrating RNA-sequencing and network analysis to explore the mechanism of topical Pien Tze Huang treatment on diabetic wounds

GZ Cao, LL Tian, JY Hou, Y Zhang, H Xu… - Frontiers in …, 2024 - frontiersin.org
Introduction: Diabetic ulcers have become one of the major complications of diabetes
mellitus (DM) and are a leading cause of death and disabling disease. However, current …

Pien Tze Huang accelerated wound healing by inhibition of abnormal fibroblast apoptosis in Streptozotocin induced diabetic mice

Y Yan, X Liu, Y Zhuang, Y Zhai, X Yang, Y Yang… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Diabetic foot ulcer is one of the most serious complications
of diabetes. Effective medical treatment regarding improvement of ulcer healing in patients is …

Quyu Shengji formula facilitates diabetic wound healing via inhibiting the expression of prostaglandin transporter

Y Lu, X Ding, F Qi, Y Ru, L Kuai, S Chen… - Evidence‐Based …, 2021 - Wiley Online Library
Background. Quyu Shengji Formula (QSF), a Chinese medicine formula widely used in the
clinic, has proven therapeutic effects on diabetic ulcers. Nevertheless, the potential …

[HTML][HTML] Huangbai liniment and berberine promoted wound healing in high-fat diet/Streptozotocin-induced diabetic rats

J Zhang, R Zhou, L Deng, G Cao, Y Zhang, H Xu… - Biomedicine & …, 2022 - Elsevier
Diabetic ulcer is a challenging complication of diabetes mellitus but current treatments
cannot achieve satisfactory results. In this study, the effect of Huangbai liniment (HB) and …

Ruyi Jinhuang Powder accelerated diabetic ulcer wound healing by regulating Wnt/β-catenin signaling pathway of fibroblasts in Vivo and in Vitro

M Wu, J Huang, J Shi, L Shi, Q Zeng, H Wang - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Diabetic ulcer is a common complication of diabetes.
Therapies of diabetic ulcer are still challenging due to the complicated aetiology. Ruyi …

[HTML][HTML] Huiyang Shengji decoction promotes wound healing in diabetic mice by activating the EGFR/PI3K/ATK pathway

Q Liu, J Zhang, X Han, J Chen, Y Zhai, Y Lin, H Ma… - Chinese Medicine, 2021 - Springer
Background Common chronic wounds include diabetic ulcers, venous ulcers, and pressure
ulcers. The traditional Chinese medicine Huiyang Shengji decoction (HYSJD) has been …

The signaling pathways of traditional Chinese medicine in promoting diabetic wound healing

X Zhou, Y Guo, K Yang, P Liu, J Wang - Journal of Ethnopharmacology, 2022 - Elsevier
Ethnopharmacological relevance The diabetic wound is one of the common chronic
complications of diabetes, which seriously affects patients' quality of life and even causes …

[HTML][HTML] The mechanism of Chebulae Fructus Immaturus promote diabetic wound healing based on network pharmacology and experimental verification

F Qiu, S Fan, Y Diao, J Liu, B Li, K Li… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Diabetic ulcers (DUs) are commonly seen in the
lower limbs, especially the feet. Long-term hyperglycaemia in diabetic patients may cause …