Pyruvate Kinase M2 Accelerates Cutaneous Wound Healing via Glycolysis and Wnt/β-Catenin Signaling
E Kim, Y Hwang, H Kim, GU Kim, YC Ryu, M Yoon… - Pharmaceutics, 2023 - mdpi.com
Cutaneous wound healing is a complex and dynamic process with high energy demand.
The activation of glycolysis is essential for restoring the structure and function of injured …
The activation of glycolysis is essential for restoring the structure and function of injured …
Efficacy and mechanism of Schisandra chinensis active component Gomisin A on diabetic skin wound healing: Network pharmacology and in vivo experimental …
Z Zhang, W Yang, J Chen, X Chen, Y Gu - Journal of Ethnopharmacology, 2024 - Elsevier
Abstract Ethnopharmacological relevance Schisandra chinensis (Turcz.) Baill., a common
traditional Chinese herbal medicine, has been used for the treatment of diabetes mellitus …
traditional Chinese herbal medicine, has been used for the treatment of diabetes mellitus …
Wu‐Mei‐Wan reduces insulin resistance via inhibition of NLRP3 inflammasome activation in HepG2 cells
X Yang, L Li, K Fang, R Dong, J Li… - Evidence‐Based …, 2017 - Wiley Online Library
Wu‐Mei‐Wan (WMW) is a Chinese herbal formula used to treat type 2 diabetes. In this study,
we aimed to explore the effects and mechanisms of WMW on insulin resistance in HepG2 …
we aimed to explore the effects and mechanisms of WMW on insulin resistance in HepG2 …
A novel hydrogel with glucose-responsive hyperglycemia regulation and antioxidant activity for enhanced diabetic wound repair
Enhanced diabetic wound repair remained a global challenge. Herein, we reported a novel
hydrogel with glucose-responsive hyperglycemia regulation and antioxidant activity for …
hydrogel with glucose-responsive hyperglycemia regulation and antioxidant activity for …
Effects of Chinese herbs for replenishing qi and resolving stagnation on hypoxia-inducible factor-1alpha and vascular endothelial growth factor in granulation tissue of …
HF Que, YY Zhu, YF Wang, Z Zhang, JN Xu… - Zhong xi yi jie he xue …, 2007 - europepmc.org
Objective To explore the effects of Chinese herbs for replenishing qi and resolving
stagnation on hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth …
stagnation on hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth …
The protective role of resveratrol in diabetic wound healing
M Bi, Y Qin, L Wang, J Zhang - Phytotherapy Research, 2023 - Wiley Online Library
Diabetic wounds are severe complications of diabetes mellitus (DM), which have difficulty in
healing. Although diverse treatments have been used, the prognosis of diabetic wounds is …
healing. Although diverse treatments have been used, the prognosis of diabetic wounds is …
Mechanisms of resveratrol against diabetic wound by network pharmacology and experimental validation
D Youjun, Y Huang, Y Lai, Z Ma, X Wang… - Annals of …, 2023 - Taylor & Francis
Background Resveratrol (RSV) that possesses anti-oxidative, anti-inflammatory, and pro-
angiogenic effects is an effective drug for diabetic wound (DW), while its pharmacological …
angiogenic effects is an effective drug for diabetic wound (DW), while its pharmacological …
Synergistic interaction between Astragali Radix and Rehmanniae Radix in a Chinese herbal formula to promote diabetic wound healing
KM Lau, KK Lai, CL Liu, JCW Tam, MH To… - Journal of …, 2012 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Astragali Radix (AR) and Rehmanniae Radix
(RR) are two traditional Chinese medicines widely used in China for treating diabetes …
(RR) are two traditional Chinese medicines widely used in China for treating diabetes …
Antidiabetic action of the Chinese formula Shouhuitongbian and the underlying mechanism associated with alteration of gut microbiota
T Wang, H Liao, J Lin, M Zhang, B Chen, R Yin, J Sun… - Phytomedicine, 2024 - Elsevier
Background The prevalence and incidence of type 2 diabetes mellitus (T2DM) have
dramatically increased. The intestinal flora and its derived metabolites are demonstrated to …
dramatically increased. The intestinal flora and its derived metabolites are demonstrated to …
20 (S)-Protopanaxadiol enhances angiogenesis via HIF-1α-mediated VEGF secretion by activating p70S6 kinase and benefits wound healing in genetically diabetic …
EY Zhang, B Gao, HL Shi, LF Huang, L Yang… - … & Molecular Medicine, 2017 - nature.com
Impaired angiogenesis is one of the crucial factors that impede the wound healing process
in diabetic foot ulcers (DFUs). In this study, we found that 20 (S)-protopanaxadiol (PPD), an …
in diabetic foot ulcers (DFUs). In this study, we found that 20 (S)-protopanaxadiol (PPD), an …