Improved prediction of fungal effector proteins from secretomes with EffectorP 2.0

J Sperschneider, PN Dodds… - Molecular plant …, 2018 - Wiley Online Library
Plant‐pathogenic fungi secrete effector proteins to facilitate infection. We describe extensive
improvements to EffectorP, the first machine learning classifier for fungal effector prediction …

EffectorP: predicting fungal effector proteins from secretomes using machine learning

J Sperschneider, DM Gardiner, PN Dodds… - New …, 2016 - Wiley Online Library
Eukaryotic filamentous plant pathogens secrete effector proteins that modulate the host cell
to facilitate infection. Computational effector candidate identification and subsequent …

[HTML][HTML] Computational prediction of effector proteins in fungi: opportunities and challenges

H Sonah, RK Deshmukh, RR Bélanger - Frontiers in plant science, 2016 - frontiersin.org
Effector proteins are mostly secretory proteins that stimulate plant infection by manipulating
the host response. Identifying fungal effector proteins and understanding their function is of …

[HTML][HTML] Evaluation of secretion prediction highlights differing approaches needed for oomycete and fungal effectors

J Sperschneider, AH Williams, JK Hane… - Frontiers in plant …, 2015 - frontiersin.org
The steadily increasing number of sequenced fungal and oomycete genomes has enabled
detailed studies of how these eukaryotic microbes infect plants and cause devastating …

EffectorP 3.0: prediction of apoplastic and cytoplasmic effectors in fungi and oomycetes

J Sperschneider, PN Dodds - Molecular plant-microbe …, 2022 - Am Phytopath Society
Many fungi and oomycete species are devasting plant pathogens. These eukaryotic
filamentous pathogens secrete effector proteins to facilitate plant infection. Fungi and …

[HTML][HTML] Effector biology of biotrophic plant fungal pathogens: Current advances and future prospects

R Jaswal, K Kiran, S Rajarammohan, H Dubey… - Microbiological …, 2020 - Elsevier
The interaction of fungal pathogens with their host requires a novel invading mechanism
and the presence of various virulence-associated components responsible for promoting the …

Bioinformatic prediction of plant–pathogenicity effector proteins of fungi

DAB Jones, S Bertazzoni, CJ Turo, RA Syme… - Current opinion in …, 2018 - Elsevier
Highlights•Review of current methods in fungal plant pathogenicity effector protein
prediction.•Recent advances have been made in structural and machine learning-based …

[HTML][HTML] Advances and challenges in computational prediction of effectors from plant pathogenic fungi

J Sperschneider, PN Dodds, DM Gardiner… - PLoS …, 2015 - journals.plos.org
Fungi occupy diverse environmental niches and many have evolved to live a pathogenic
lifestyle, causing devastating diseases in plants and animals. The interface between host …

[HTML][HTML] Prediction of effector protein structures from fungal phytopathogens enables evolutionary analyses

K Seong, KV Krasileva - Nature Microbiology, 2023 - nature.com
Elucidating the similarity and diversity of pathogen effectors is critical to understand their
evolution across fungal phytopathogens. However, rapid divergence that diminishes …

In silico characterization and molecular evolutionary analysis of a novel superfamily of fungal effector proteins

I Stergiopoulos, YAI Kourmpetis, JC Slot… - Molecular Biology …, 2012 - academic.oup.com
Most fungal plant pathogens secrete effector proteins during pathogenesis to manipulate
their host's defense and promote disease. These are so highly diverse in sequence and …