NLRP3 inflammasome has been reported to be associated with inflammatory bowel disease
including colitis due to its potential ability to induce IL-1β secretion. Emerging studies have …

Emerging evidence suggests that NLRP3 inflammasome was associated with various kinds
of immunological diseases including colitis. However, there are few drugs targeting …

NLRP3 inflammasome is a novel therapeutic target for inflammatory bowel disease (IBD).
The aim of this study was to investigate the anti-inflammatory effect of a bioactive flavonoid …

Previous studies reported that Ginsenoside Rd (Rd) had anti-inflammatory and anti-cancer
effects. However, the molecular mechanism underlying the inhibition effect of Rd on colitis in …

Background. Inflammatory responses induced by intestinal ischemia‐reperfusion (IIR) lead
to serious systemic organ dysfunction and pose a challenge for current treatment. This study …

Background: Ulcerative colitis (UC) is a chronic recurrent inflammatory bowel disease (IBD).
The conventional drugs for UC may induce severe side effects. Herbal medicine is …

Background NLRP3 inflammasome mediates IL-1β maturation, therefore plays a vital role in
the development of IBD. Curcumin is known for possessing strong anti-inflammatory …

Ulcerative colitis is a chronic and recurrent inflammatory bowel disease mediated by
immune response. Geniposide is the main active ingredient extracted from Gardenia …

Ongoing research explores the underlying causes of ulcerative colitis and Crohn's disease.
Many experts suggest that dysbiosis in the gut microbiota and genetic, immunological, and …

Soy isoflavones (SIFs) are selective estrogen receptor modulators (SERMs) that have anti-
inflammatory activities. Our previous study found that estrogen receptor α (ERα) directly …