Oroxindin is a flavonoid isolated from the traditional Chinese medicine Huang-Qin, which
has shown various pharmacological activities including anti-inflammatory, antitumor …

Loganin, a major bioactive iridoid glycoside derived from Cornus officinalis, exerts different
beneficial biological properties. Recently, loganin has been reported to exhibit potential anti …

Astragalus polysaccharide is an important bioactive component of Astragalus
membranaceus, an herb used in traditional Chinese medicine for treating inflammatory …

Management of inflammatory bowel disease (IBD) is a real clinical challenge. Despite
intense investigation, the mechanisms of IBD remain substantially unidentified. Some …

Aberrant activation of NLRP3 inflammasome has been implicated in a variety of human
inflammatory diseases, but currently, no pharmacological NLRP3 inhibitor has been …

Ulcerative colitis (UC) has become a global disease and closely related to changes in
intestinal oxidative stress, inflammatory factors and gut microbiota. Furthermore, the NLRP3 …

Intestine microbial products may translocate into the liver via portal vein and trigger or
exacerbate hepatocyte inflammatory responses during liver injury. The NLRP3 …

Objective and design Inflammatory bowel disease (IBD) is known to cause chronic
inflammation in the digestive tract by the immune malfunction. Herein, we demonstrate the …

Ulcerative colitis (UC), one of the foremost common forms of inflammatory bowel disease,
poses a serious threat to human health. Currently, safe and effective treatments are not …

Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, has
increased in incidence and prevalence in recent decades. Both clinical and animal studies …