Response to methylphenidate in adults with ADHD is associated with a polymorphism in SLC6A3 (DAT1)
JS Kooij, AM Boonstra, SH Vermeulen… - American Journal of …, 2008 - Wiley Online Library
In this pharmacogenetic study in adults with ADHD (n= 42), a stratified analysis was
performed of the association between response to methylphenidate (MPH), assessed under …
performed of the association between response to methylphenidate (MPH), assessed under …
Association of dopamine, serotonin, and nicotinic gene polymorphisms with methylphenidate response in ADHD
H Tharoor, EA Lobos, RD Todd… - American Journal of …, 2008 - Wiley Online Library
Gene polymorphisms of the 3′ untranslated region (3′‐UTR) of the dopamine transporter
(DAT1), Dopamine receptor exon 3 D4 variable number tandem repeat (DRD4VNTR) …
(DAT1), Dopamine receptor exon 3 D4 variable number tandem repeat (DRD4VNTR) …
Meta-analysis of the association between dopamine transporter genotype and response to methylphenidate treatment in ADHD
Attention-deficit/hyperactivity disorder (ADHD) is a prevalent childhood-onset
neuropsychiatric disorder. Treatment with methylphenidate, which blocks dopamine and …
neuropsychiatric disorder. Treatment with methylphenidate, which blocks dopamine and …
Polymorphisms of the dopamine transporter gene: influence on response to methylphenidate in attention deficit-hyperactivity disorder
Attention deficit-hyperactivity disorder (ADHD) is a very common and heterogeneous
childhood-onset psychiatric disorder, affecting between 3% and 5% of school age children …
childhood-onset psychiatric disorder, affecting between 3% and 5% of school age children …
Pharmacogenetics of methylphenidate response in attention deficit/hyperactivity disorder: Association with the dopamine transporter gene (SLC6A3)
D Purper‐Ouakil, M Wohl, S Orejarena… - American Journal of …, 2008 - Wiley Online Library
Pharmacogenetic studies investigating the 40‐bp VNTR polymorphism at SLC6A3 and
methylphenidate response have shown conflicting results and large differences in study …
methylphenidate response have shown conflicting results and large differences in study …
No significant association between genetic variants in 7 candidate genes and response to methylphenidate treatment in adult patients with ADHD
V Contini, MM Victor, GP Bertuzzi… - Journal of clinical …, 2012 - journals.lww.com
Results from pharmacogenetic investigations of methylphenidate (MPH) response in
patients with ADHD are still inconsistent, especially among adults. This study investigates …
patients with ADHD are still inconsistent, especially among adults. This study investigates …
Absence of association with DAT1 polymorphism and response to methylphenidate in a sample of adults with ADHD
E Mick, J Biederman, T Spencer… - American Journal of …, 2006 - Wiley Online Library
A polymorphism in the dopamine transporter gene (DAT1) has been previously associated
with ADHD and methylphenidate has been hypothesized to block the dopamine transporter …
with ADHD and methylphenidate has been hypothesized to block the dopamine transporter …
[HTML][HTML] Dopamine transporter 3′-UTR VNTR genotype and ADHD: a pharmaco-behavioural genetic study with methylphenidate
R Joober, N Grizenko, S Sengupta, LB Amor… - …, 2007 - nature.com
We sought to test the hypothesis that the variable number of tandem repeat (VNTR)
polymorphism in the 3′-untranslated region (3′-UTR) of the SLC6A3 gene modulates …
polymorphism in the 3′-untranslated region (3′-UTR) of the SLC6A3 gene modulates …
Dopamine transporter genotype and stimulant side effect factors in youth diagnosed with attention-deficit/hyperactivity disorder
R Gruber, R Joober, N Grizenko… - Journal of Child and …, 2009 - liebertpub.com
The dopamine transporter locus (DAT1) has been studied as a risk factor for attention-
deficit/hyperactivity disorder (ADHD) and in pharmacogenetic studies of stimulant response …
deficit/hyperactivity disorder (ADHD) and in pharmacogenetic studies of stimulant response …
[HTML][HTML] Dopamine transporter genotype and methylphenidate dose response in children with ADHD
MA Stein, ID Waldman, CS Sarampote… - …, 2005 - nature.com
Stimulant medications, such as methylphenidate (MPH), are the most commonly used,
effective treatment for ADHD. MPH acts primarily by inhibiting the dopamine transporter …
effective treatment for ADHD. MPH acts primarily by inhibiting the dopamine transporter …