Inhibitory effects of resveratrol on foam cell formation are mediated through monocyte chemotactic protein-1 and lipid metabolism-related proteins

W Dong, X Wang, S Bi, Z Pan… - International …, 2014 - spandidos-publications.com
Resveratrol has been shown to exert anti-atherosclerotic effects. 5'AMP-activated protein
kinase (AMPK) and monocyte chemotactic protein-1 (MCP-1) play key roles in foam cell …

[HTML][HTML] Quercetin increases macrophage cholesterol efflux to inhibit foam cell formation through activating PPARγ-ABCA1 pathway

L Sun, E Li, F Wang, T Wang, Z Qin… - International journal of …, 2015 - ncbi.nlm.nih.gov
The accumulation of cholesterol in macrophages could induce the formation of foam cells
and increase the risk of developing atherosclerosis. We wonder if quercetin, one of …

Retracted: Resveratrol Derivative, Trans‐3, 5, 4′‐Trimethoxystilbene, Prevents the Developing of Atherosclerotic Lesions and Attenuates Cholesterol Accumulation …

M Hong, J Li, S Li, MM Almutairi - Molecular nutrition & food …, 2020 - Wiley Online Library
Scope Recent studies have demonstrated that trans‐3, 5, 4′‐Trimethoxystilbene (TMS), a
novel derivative of resveratrol, may suppress the foam cells formation and restrain …

Metformin suppresses foam cell formation, inflammation and ferroptosis via the AMPK/ERK signaling pathway in ox‑LDL‑induced THP‑1 monocytes

Y Zhao, Y Zhao, Y Tian, Y Zhou - Experimental and …, 2022 - spandidos-publications.com
Numerous studies have shown that the formation of foam cells is of vital importance in the
process of atherosclerosis. The aim of the present study was to assess the effects of …

Resveratrol inhibits foam cell formation via NADPH oxidase 1-mediated reactive oxygen species and monocyte chemotactic protein-1

DW Park, K Baek, JR Kim, JJ Lee, SH Ryu… - … & molecular medicine, 2009 - nature.com
Resveratrol is a polyphenolic compound in red wine that has anti-oxidant and
cardioprotective effects in animal models. Reactive oxygen species (ROS) and monocyte …

Three polymethoxyflavones from the peel of Citrus reticulata “Chachi” inhibits oxidized low-density lipoprotein-induced macrophage-derived foam cell formation

PL Liang, QW Liang, PW He, XL Chen, Y Xu… - Frontiers in …, 2022 - frontiersin.org
Foam cell formation is the hallmark of the development and progression of atherosclerosis.
The aim of this study was to investigate the regulatory effects of three polymethoxyflavones …

Bioactive components to inhibit foam cell formation in atherosclerosis

S Singh, S Changkija, R Mudgal… - Molecular Biology …, 2022 - Springer
Background The production of lipid-laden cells in macrophages after significant ingestion of
oxidized low-density lipoprotein is considered the most critical phase in the creation of …

Hydroxytyrosol Reduces Foam Cell Formation and Endothelial Inflammation Regulating the PPARγ/LXRα/ABCA1 Pathway

S Franceschelli, F De Cecco, M Pesce, P Ripari… - International journal of …, 2023 - mdpi.com
Cholesterol accumulation in macrophages leads to the formation of foam cells and
increases the risk of developing atherosclerosis. We have verified whether hydroxytyrosol …

The anti-atherogenic effects of berberine on foam cell formation are mediated through the upregulation of sirtuin 1

L Chi, L Peng, N Pan, X Hu… - … journal of molecular …, 2014 - spandidos-publications.com
Berberine (BBR) is a botanical alkaloid that has been reported to have effects in
cardiovascular diseases; however, the mechanisms involved are not yet fully understood. In …

Simvastatin inhibited oxLDL-induced proatherogenic effects through calpain-1–PPARγ–CD36 pathway

X Yang, M Yin, L Yu, M Lu, H Wang… - Canadian Journal of …, 2016 - cdnsciencepub.com
We previously reported that simvastatin, an inhibitor of HMG-CoA reductase, inhibits
atherosclerosis in rats. The present study was designed to investigate the effect of …