It has been increasingly recognized that tumor microenvironment plays an important role in
carcinogenesis. Inflammatory component is present and contributes to tumor proliferation …

Inflammation, especially chronic inflammation, plays a pivotal role in tumorigenesis and
metastasis through various mechanisms and is now recognized as a hallmark of cancer and …

Lung cancer is the leading cause of cancer mortality worldwide, and at only 18%, it has one
of the lowest 5-year survival rates of all malignancies. With its highly complex mutational …

Objectives In non‐small cell lung cancer (NSCLC), the immune system and possibly its
composition affect survival. In this in silico study, the immune infiltrate composition in NSCLC …

Purpose Cancer cells, despite stemming from the own cells of their host, usually elicit an
immune response. This response usually enables elimination of cancer at its earliest stages …

Inflammation has accompanied human beings since the emergence of wounds and
infections. In the past decades, numerous efforts have been undertaken to explore the …

Purpose Inflammation plays a critical role in cancer progression. In this study we investigate
the pro-tumorigenic activities and gene expression profiles of lung cancer cells after …

Lung cancer has the highest incidence of morbidity and mortality throughout the globe. A
large number of patients are diagnosed with lung cancer at the later stages of the disease …

Chronic inflammatory mediators exert pleiotropic effects in the development of cancer. On
the one hand, inflammation favors carcinogenesis, malignant transformation, tumor growth …

Although the lung is the most common metastatic site for cancer cells, biologic mechanisms
regulating lung metastasis are not fully understood. Using heterotopic and intravenous …