Inflammation: a driving force speeds cancer metastasis
Y Wu, BP Zhou - Cell cycle, 2009 - Taylor & Francis
It has been increasingly recognized that tumor microenvironment plays an important role in
carcinogenesis. Inflammatory component is present and contributes to tumor proliferation …
carcinogenesis. Inflammatory component is present and contributes to tumor proliferation …
Inflammation-induced tumorigenesis and metastasis
S Hibino, T Kawazoe, H Kasahara, S Itoh… - International journal of …, 2021 - mdpi.com
Inflammation, especially chronic inflammation, plays a pivotal role in tumorigenesis and
metastasis through various mechanisms and is now recognized as a hallmark of cancer and …
metastasis through various mechanisms and is now recognized as a hallmark of cancer and …
Macrophages, inflammation, and lung cancer
EM Conway, LA Pikor, SHY Kung… - American journal of …, 2016 - atsjournals.org
Lung cancer is the leading cause of cancer mortality worldwide, and at only 18%, it has one
of the lowest 5-year survival rates of all malignancies. With its highly complex mutational …
of the lowest 5-year survival rates of all malignancies. With its highly complex mutational …
Immune microenvironment composition in non‐small cell lung cancer and its association with survival
M Tamminga, TJN Hiltermann… - Clinical & …, 2020 - Wiley Online Library
Objectives In non‐small cell lung cancer (NSCLC), the immune system and possibly its
composition affect survival. In this in silico study, the immune infiltrate composition in NSCLC …
composition affect survival. In this in silico study, the immune infiltrate composition in NSCLC …
Cancer-associated inflammation: pathophysiology and clinical significance
P Pęczek, M Gajda, K Rutkowski, M Fudalej… - Journal of cancer …, 2023 - Springer
Purpose Cancer cells, despite stemming from the own cells of their host, usually elicit an
immune response. This response usually enables elimination of cancer at its earliest stages …
immune response. This response usually enables elimination of cancer at its earliest stages …
Targeting inflammation as cancer therapy
M Wang, S Chen, X He, Y Yuan, X Wei - Journal of Hematology & …, 2024 - Springer
Inflammation has accompanied human beings since the emergence of wounds and
infections. In the past decades, numerous efforts have been undertaken to explore the …
infections. In the past decades, numerous efforts have been undertaken to explore the …
Tumor-associated macrophages: the double-edged sword in cancer progression
JJW Chen, YC Lin, PL Yao, A Yuan… - Journal of clinical …, 2005 - ascopubs.org
Purpose Inflammation plays a critical role in cancer progression. In this study we investigate
the pro-tumorigenic activities and gene expression profiles of lung cancer cells after …
the pro-tumorigenic activities and gene expression profiles of lung cancer cells after …
Immunotherapy and targeted therapy for lung cancer: Current status and future perspectives
Lung cancer has the highest incidence of morbidity and mortality throughout the globe. A
large number of patients are diagnosed with lung cancer at the later stages of the disease …
large number of patients are diagnosed with lung cancer at the later stages of the disease …
Chronic inflammation in cancer development
G Multhoff, M Molls, J Radons - Frontiers in immunology, 2012 - frontiersin.org
Chronic inflammatory mediators exert pleiotropic effects in the development of cancer. On
the one hand, inflammation favors carcinogenesis, malignant transformation, tumor growth …
the one hand, inflammation favors carcinogenesis, malignant transformation, tumor growth …
Interleukin-5 facilitates lung metastasis by modulating the immune microenvironment
R Zaynagetdinov, TP Sherrill, LA Gleaves, AG McLoed… - Cancer research, 2015 - AACR
Although the lung is the most common metastatic site for cancer cells, biologic mechanisms
regulating lung metastasis are not fully understood. Using heterotopic and intravenous …
regulating lung metastasis are not fully understood. Using heterotopic and intravenous …