The sympathetic control of blood pressure

PG Guyenet - Nature Reviews Neuroscience, 2006 - nature.com
Hypertension—the chronic elevation of blood pressure—is a major human health problem.
In most cases, the root cause of the disease remains unknown, but there is mounting …

The role of the autonomic nervous system in hypertension

J Amerena, S Julius - Hypertension Research, 1995 - jstage.jst.go.jp
The role of the autonomic nervous system in the genesis and maintenance of hypertension
is becoming clearer with time. Early research suggested that increased vascular resistance …

The sympathetic neurobiology of essential hypertension: disparate influences of obesity, stress, and noradrenaline transporter dysfunction?

M Esler, M Rumantir, D Kaye… - American journal of …, 2001 - academic.oup.com
Although the importance of sympathetic nervous activation in the pathogenesis of essential
hypertension is well documented, the exact pathophysiology of the sympathetic nervous …

Sympathetic nervous system and hypertension: New evidences

G Seravalle, G Grassi - Autonomic Neuroscience, 2022 - Elsevier
Evidences collected in the past few years have strengthened the concept that the
sympathetic nervous system plays a primary role in the development and progression of the …

A sympathetic view of the sympathetic nervous system and human blood pressure regulation

MJ Joyner, N Charkoudian… - Experimental physiology, 2008 - Wiley Online Library
New ideas about the relative importance of the autonomic nervous system (and especially
its sympathetic arm) in long‐term blood pressure regulation are emerging. It is well known …

Point: Chronic activation of the sympathetic nervous system is the dominant contributor to systemic hypertension

M Esler, E Lambert, M Schlaich - Journal of Applied …, 2010 - journals.physiology.org
For the past three decades, the renin-angiotensin system has been the major focus in high
blood pressure research. The proven value of antihypertensive drugs that block this system …

Evidence for increased noradrenaline release from subcortical brain regions in essential hypertension

C Ferrier, GL Jennings, G Eisenhofer… - Journal of …, 1993 - journals.lww.com
Objective: To test whether the activation of the sympathetic nervous system that is common
in essential hypertension derives from subcortical noradrenergic neuronal excitation. Design …

Sympathetic activity, vascular capacitance, and long-term regulation of arterial pressure

GD Fink - Hypertension, 2009 - Am Heart Assoc
ran was both a brilliant scientist and one of the founding fathers in the field of hypertension
research, but I am particularly gratified to join the list of superb scientists who have preceded …

The human sympathetic nervous system: its relevance in hypertension and heart failure

G Parati, M Esler - European heart journal, 2012 - academic.oup.com
Evidence assembled in this review indicates that sympathetic nervous system dysfunction is
crucial in the development of heart failure and essential hypertension. This takes the form of …

Interactions between the sympathetic nervous system and the kidneys in arterial hypertension

O Grisk, R Rettig - Cardiovascular research, 2004 - academic.oup.com
Elevated sympathetic activity changes renal function and accelerates the development of
hypertension. Principles of sympatho-renal interactions in chronic hypertension are …