Essential hypertension is thought to be caused by both genetic and environmental factors,
with varying combinations in different individuals. Proposed environmental factors include …

Sympathetic factors play a central role not only in cardiovascular homeostatic control but
also in the pathogenesis and/or in the progression of several cardiovascular diseases, such …

The relationship between plasma levels of norepinephrine (NE) and sympathetic neural
activity is discussed with special reference to human primary hypertension. Since …

IN ESTABLISHED human hypertension, there has never been any real doubt that the
baroreceptor mechanisms remain active, hut regulate the arterial pressure to a new high …

The sympathetic nervous system plays a pivotal role in the long-term regulation of arterial
blood pressure through the ability of the central nervous system to integrate neurohumoral …

To determine if an abnormality exists in the sympathetic nervous system of patients with
accelerated hypertension, we recorded muscle sympathetic nerve activity (MSNA) from the …

Increased sympathetic tone is found in about 30% of patients with hypertension. This
abnormality is closely associated with the metabolic syndrome of dyslipidaemia and …

The sympathetic overdrive that characterizes essential hypertension is potentiated when left
ventricular hypertrophy or congestive heart failure is detected. No information exists …

It is now well accepted that many forms of experimental hypertension and human essential
hypertension are caused by increased activity of the sympathetic nervous system. However …

Numerous experimental and clinical studies, using various approaches to evaluate the
release of sympathetic transmitters and to obtain sympathetic nerve microneurographic …