Although the definitive cause of primary hypertension remains unknown, significant
advances have been made in understanding its pathogenesis and its clinical physiology …

The autonomic nervous system and its sympathetic arm play important roles in the
regulation of blood pressure. 1–3 Their role in the short-term regulation of blood pressure …

To determine whether sympathetic hyperactivity of hypothalamic origin contributes to keep
blood pressures high in spontaneous hypertension, aortic pressures and sympathetic nerve …

Spike potentials in abdominal sympathetic nerves were recorded together with aortic blood
pressure before and during electrical stimulation of the posterior hypothalamus in urethane …

Recordings of sympathetic activity from multifibre preparations of renal nerves have
produced conflicting results concerning the presence or absence of an increased …

The mechanism of sustained hypertension in spontaneously hypertensive rats has not been
elucidated. In the present investigation, vasoconstrictor responses to a variety of neurogenic …

Essential hypertension is a multifactorial disorder with a strong genetic predisposition.
Although anti-hypertensive medications have drastically reduced cardiovascular diseases …

The sympathetic nervous system plays a critical role in the pathogenesis of hypertension.
The central nervous system (CNS) organizes the sympathetic outflow and various inputs …

The classical neurotransmitters, glutamate and GABA, mediate fast (milliseconds) synaptic
transmission and modulate its effectiveness through slow (seconds to minutes) signaling …

A high incidence of acute cardiovascular events and sudden cardiac death following
unexpected acute emotional stress or a natural catastrophic disaster has been well …