Near-infrared spectroscopy: does it function in functional activation studies of the adult brain?

H Obrig, R Wenzel, M Kohl, S Horst, P Wobst… - International Journal of …, 2000 - Elsevier
Changes in optical properties of biological tissue can be examined by near-infrared
spectroscopy (NIRS). The relative transparency of tissues including the skull to near-infrared …

Activation of visual cortex imaged by 24 channel near-infrared spectroscopy

K Takahashi, S Ogata, R Yamamoto… - … of biomedical optics, 2000 - spiedigitallibrary.org
Near-infrared spectroscopy (NIRS) is a noninvasive technique for continuous monitoring of
the amounts of total hemoglobin (total-Hb), oxygenated hemoglobin,(oxy-Hb) and …

Functional near-infrared spectroscopy (fNIRS): principles and neuroscientific applications

J León-Carrión, U León-Domínguez - Neuroimaging methods, 2012 - books.google.com
1. Introduction fNIRS is a device designed to detect changes in the concentration of
oxygenated (oxyHb) and deoxygenated (deoxyHb) haemoglobin molecules in the blood, a …

Functional near‐infrared spectroscopy: potential and limitations in neuroimaging studies

Y Hoshi - International Review of Neurobiology, 2005 - Elsevier
Near‐infrared spectroscopy (NIRS), a noninvasive optical technique, can measure changes
in hemoglobin (Hb) concentrations in brain tissue. Jöbsis first described the in vivo …

Beyond the visible—imaging the human brain with light

H Obrig, A Villringer - Journal of Cerebral Blood Flow & …, 2003 - journals.sagepub.com
Optical approaches to investigate cerebral function and metabolism have long been applied
in invasive studies. From the neuron cultured in vitro to the exposed cortex in the human …

Linear aspects of changes in deoxygenated hemoglobin concentration and cytochrome oxidase oxidation during brain activation

P Wobst, R Wenzel, M Kohl, H Obrig, A Villringer - Neuroimage, 2001 - Elsevier
We used near infrared spectroscopy (NIRS) to investigate the vascular and metabolic
response to brain activation in human primary and adjacent secondary visual cortex. NIRS is …

Near infrared spectroscopy (NIRS): a new tool to study hemodynamic changes during activation of brain function in human adults

A Villringer, J Planck, C Hock, L Schleinkofer… - Neuroscience …, 1993 - Elsevier
In healthy human adults, cerebral concentrations of oxygenated hemoglobin ([HbO 2]) and
deoxygenated hemoglobin ([HbR]) were assessed during brain activation using near …

Non-invasive optical spectroscopy and imaging of human brain function

A Villringer, B Chance - Trends in neurosciences, 1997 - cell.com
Brain activity is associated with changes in optical properties of brain tissue. Optical
measurements during brain activation can assess haemoglobin oxygenation, cytochrome-c …

Assessment of local brain activation: A simultaneous PET and near-infrared spectroscopy study

K Villringer, S Minoshima, C Hock, H Obrig… - Optical Imaging of Brain …, 1997 - Springer
In five healthy human subjects, near-infrared spectroscopy (NIRS) and positron emission
tomography (PET) examinations were performed simultaneously. Changes in [oxy …

Noninvasive assessment of cerebral hemodynamics and tissue oxygenation during activation of brain cell function in human adults using near infrared spectroscopy

A Villringer, J Planck, S Stodieck, K Bötzel… - Oxygen Transport to …, 1994 - Springer
Abstract Near Infrared Spectroscopy (NIRS) is an optical technique that measures tissue
absorbance of light at several wavelengths in the 700-1000 nm spectral region. From the …